Anticipating disaster: the genetics of familial pancreatic cancer

Lerch, M. M.
February 2006
Gut;Feb2006, Vol. 55 Issue 2, p150
Academic Journal
To be born into a family with familial pancreatic cancer, an inheritable, autosomal dominant disorder, has various implications for an individual's life—and none is fortunate. The prospects lust turned even darker because of ‘anticipation’, the phenomenon that successive generations are affected by an inheritable disorder at a progressively earlier age. An up to date study shows that ‘anticipation’ is also operative in familial pancreatic cancer, meaning that affected children die approximately 10 years earlier than their affected parents.


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