TITLE

Can modulating corticotropin releasing hormone receptors alter visceral sensitivity?

AUTHOR(S)
Fukudo, S.; Saito, K.; Sagami, Y.; Kanazawa, M.
PUB. DATE
February 2006
SOURCE
Gut;Feb2006, Vol. 55 Issue 2, p146
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Activation of corticotropin releasing hormone (CRH) receptor 2 (CRH-R2) reduces visceral sensitivity induced by colorectal distension in conscious rats. This finding is relevant to the increased interest in the potential use of therapeutic agents that act on CRH receptors in the treatment of irritable bowel syndrome
ACCESSION #
19552420

 

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