Occupational exposures and non-Hodgkin lymphoma: where do we stand?

Blair, A.
January 2006
Occupational & Environmental Medicine;Jan2006, Vol. 63 Issue 1, p1
Academic Journal
The article focuses on factors leading to the rise in incidence of non-Hodgkin lymphoma (NHL). The rise does not appear to be due to diagnostic changes and it cannot be strictly due to genetic factors because gene frequencies do not change rapidly enough to cause such large changes in rates over such a short period of time. It is thus expected to be due to changes in the level or distribution of environmental factors. Possible environmental risk factors include occupational and environmental chemicals, microbes, diet, physical inactivity, and other lifestyle factors. Researchers studied new environmental risk factors for NHL and found that elevated risks for NHL are associated with several occupations and industries. They concluded that exposure assessment techniques for case-control studies display a disappointing performance with regard to validity. Exposure assessment in cohort studies may be better, but considerable improvement is necessary to be able to identify small to moderate levels of risk.


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