Vena cava filters reduced long-term risk for pulmonary embolism in proximal deep venous thrombosis: COMMENTARY

Hirsh, Jack
January 2006
ACP Journal Club;Jan/Feb2006, Vol. 144 Issue 1, p18
Academic Journal
This article presents comments of the author on a clinical study which showed that inferior vena cava (IVC) filters reduced long-term risk for pulmonary embolism (PE) in proximal deep venous thrombosis (DVT). Conservative indications for insertion of a permanent IVC filter in patients with acute proximal DVT or PE include a contraindication for anticoagulants and, less commonly, recurrent venous thromboembolism that occurs despite "adequate" anticoagulant therapy. The results showed that IVC filter placement reduced risk for symptomatic PE but at the cost of increased risk for recurrent DVT. 35% of patients in both groups received vitamin K antagonists for the 8-year period of follow-up, and more recurrences occurred when patients were off rather than on anticoagulant therapy.


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