Review: Evidence of benefit for perioperative β-blockers in noncardiac surgery is unreliable: COMMENTARY

Kalra, Savita; Kitchens, James
January 2006
ACP Journal Club;Jan/Feb2006, Vol. 144 Issue 1, p17
Academic Journal
This article comments on the efficacy of perioperative β-blockers in noncardiac surgery. Researchers have shown that about 1.4% of patients having noncardiac surgery will experience an adverse cardiovascular event. Experts have recommended β-blockers for at-risk patients to minimize the risk for perioperative cardiac events. However, several trials of perioperative β-blockers failed to show any significant benefit. A recent observational study suggests that β-blockers may be protective in patients at high risk for adverse events, neutral in intermediate-risk patients, and possibly harmful in low-risk patients.


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