TITLE

Review: Evidence of benefit for perioperative β-blockers in noncardiac surgery is unreliable

PUB. DATE
January 2006
SOURCE
ACP Journal Club;Jan/Feb2006, Vol. 144 Issue 1, p17
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
This article focuses on the efficacy of perioperative β-blockers in noncardiac surgery. Studies were selected if they were randomized controlled trials (RCTs) that assessed β-blockers in patients having noncardiac surgery. RCTs were excluded if there was no control group that received placebo or usual care or if no relevant events occurred in the treatment and control groups. 22 RCTS met the selection criteria. Perioperative β-blocker treatment ranged from brief intravenous β-blocker therapy just before surgery to 30-day postoperative β-blocker use. Perioperative β-blockers did not reduce any individual outcome and increased bradycardia and hypotension that required treatment.
ACCESSION #
19516003

 

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