TITLE

Review: Vitamin D plus calcium, but not vitamin D alone, prevents osteoporotic fractures in older persons: COMMENTARY

AUTHOR(S)
Johnell, Olof
PUB. DATE
January 2006
SOURCE
ACP Journal Club;Jan/Feb2006, Vol. 144 Issue 1, p14
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
This article comments on the efficacies of Vitamin D and calcium in preventing osteoporotic fractures in older persons. It has long been known that calcium and vitamin D are important to bone, but it is uncertain whether vitamin D alone is enough. Interestingly, calcium or vitamin D is recommended in all guidelines, either alone, combined, or in addition to a bone-active drug. Researchers reviewed 38 trials assessing vitamin D and vitamin D analogues for prevention of fractures associated with postmenopausal osteoporosis. The main finding was that vitamin D alone showed no statistically significant reduction in hip fractures. The conclusion is that frail older persons confined to institutions may sustain fewer hip fractures and other nonvertebral fractures if given vitamin D with calcium supplements.
ACCESSION #
19515998

 

Related Articles

  • VITAMIN D, CALCIUM SUPPLEMENTS DO NOT PREVENT FRACTURES IN ELDERLY. Lund, Amy E. // Journal of the American Dental Association (JADA);Jun2005, Vol. 136 Issue 6, p725 

    Reports on the ineffectiveness of giving elderly people regular vitamin D and calcium supplements to prevent secondary bone fractures, according to a randomized clinical trial published in the online edition of "The Lancet." Risk of elderly people who have osteoporosis to experience bone...

  • Osteoporosis treatment and fracture incidence: the ICARO longitudinal study. Adami, S.; Isaia, G.; Luisetto, G.; Minisola, S.; Sinigaglia, L.; Silvestri, S.; Agnusdei, S.; Gentilella, R.; Nuti, R. // Osteoporosis International;Aug2008, Vol. 19 Issue 8, p1219 

    None of the available osteoporosis therapies completely abolish the risk of fracture. Among 862 patients on treatment with antiresorptive agents (alendronate, risedronate, and raloxifene) for >1 year a fragility fracture was observed in 9.5%/year. This incidence is considerably higher than that...

  • Half of the patients with an acute hip fracture suffer from hypovitaminosis D: a prospective study in southeastern Finland. Nurmi, Ilona; Kaukonen, Juha-Pekka; Lü thje, Peter; Naboulsi, Helena; Tanninen, Salla; Kataja, Matti; Kallio, Maija-Leena; Leppilampi, Marjatta // Osteoporosis International;Dec2005, Vol. 16 Issue 12, p2018 

    Vitamin D deficiency may be one important contributing risk factor for an osteoporotic fracture among elderly. We analyzed serum 25-hydroxyvitamin D [S-25(OH)D] status in patients with an acute hip fracture in southeastern Finland (61°N). Consecutive patients with a fresh hip fracture ( n...

  • Review: Vitamin D plus calcium, but not vitamin D alone, prevents osteoporotic fractures in older persons.  // ACP Journal Club;Jan/Feb2006, Vol. 144 Issue 1, p14 

    This article focuses on the efficacies of Vitamin D and calcium in preventing osteoporotic fractures in older persons. Randomized and quasi-randomized controlled trials (RCTs) that compared vitamin D or a vitamin D analogue with placebo, no intervention, or calcium alone in postmenopausal women...

  • Review: vitamin D plus calcium, but not vitamin D alone, prevents osteoporotic fractures in older people. Avenell, A.; Gillespie, W. J.; Gillespie, L. D. // Evidence Based Medicine;Feb2006, Vol. 11 Issue 1, p13 

    The article reports on a study which reviews various research to determine whether supplementation with vitamin D, with or without calcium, can decrease the incidence of fractures in older people. These studies were randomized and quasi-randomized controlled trials. Findings indicated that...

  • Commentary. Johnell, Olof // Evidence Based Medicine;Feb2006, Vol. 11 Issue 1, p13 

    The article comments on a study by A. Avenell and colleagues which reviews various research to determine whether supplementation with vitamin D, with or without calcium, can decrease the incidence of fractures in older people. The positive effect of vitamin D and calcium appears to be limited to...

  • Vitamin D3, calcium, or both did not prevent secondary fractures in older persons.  // ACP Journal Club;Nov/Dec2005, Vol. 143 Issue 3, p74 

    This article presents information on a clinical study according to which vitamin D3, calcium, or both did not prevent secondary fractures in older persons. The study explored in older persons with a previous low-trauma fracture, how do vitamin D3, calcium, or both compare for preventing...

  • Association between Screening for Osteoporosis and the Incidence of Hip Fracture. Kern, Lisa M.; Powe, Neil R.; Levine, Michael A.; Fitzpatrick, Annette L.; Harris, Tamara B.; Robbins, John; Fried, Linda P. // Annals of Internal Medicine;2/1/2005, Vol. 142 Issue 3, p173 

    Background: Because direct evidence for the effectiveness of screening is lacking, guidelines disagree on whether people should be screened for osteoporosis. Objective: To determine whether population-based screening for osteoporosis in older adults is associated with fewer incident hip...

  • Prevention of Fractures in Older People with Calcium and Vitamin D. Nowson, Caryl A. // Nutrients;Sep2010, Vol. 2 Issue 9, p975 

    The greatest cause of fracture in older people is osteoporosis which contributes to increased morbidity and mortality in older people. A number of meta-analyses have been performed assessing the effectiveness of calcium supplementation alone, vitamin D supplementation alone and the combined...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics