TITLE

Review: Vitamin D plus calcium, but not vitamin D alone, prevents osteoporotic fractures in older persons

PUB. DATE
January 2006
SOURCE
ACP Journal Club;Jan/Feb2006, Vol. 144 Issue 1, p14
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
This article focuses on the efficacies of Vitamin D and calcium in preventing osteoporotic fractures in older persons. Randomized and quasi-randomized controlled trials (RCTs) that compared vitamin D or a vitamin D analogue with placebo, no intervention, or calcium alone in postmenopausal women or men were analyzed. Studies involving corticosteroid therapy were excluded. 38 RCTs met the selection criteria. Vitamin D alone did not prevent hip, vertebral, or any fracture more than placebo or no treatment. Vitamin D plus calcium prevented hip and nonvertebral fractures more than placebo or no treatment, but not more than calcium alone.
ACCESSION #
19515997

 

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