TITLE

1 year of alendronate after 1 year of parathyroid hormone (1-84) treatment increased bone mineral density in osteoporosis

PUB. DATE
January 2006
SOURCE
ACP Journal Club;Jan/Feb2006, Vol. 144 Issue 1, p10
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
This article focuses on a study conducted to examine the efficacies of alendronate and parathyroid hormone in increasing bone mineral density (BMD) in osteoporosis. Randomized controlled trial was conducted on 238 postmenopausal women 55 to 85 years of age who had osteoporosis. At 24 months, BMD at the lumber spine increased in all 4 groups. BMD at the femoral neck and total hip increased in all groups. Volumetric BMD in trabecular bone at the spine and the hip increased in all 4 groups. Small decreases in volumetric BMD in cortical bone at the hip occurred in all 4 groups. Groups did not differ for clinical fracture and adverse events.
ACCESSION #
19515991

 

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