Lamotrigine or gabapentin was better tolerated than carbamazepine in new-onset geriatric epilepsy

January 2006
ACP Journal Club;Jan/Feb2006, Vol. 144 Issue 1, p6
Academic Journal
This article present a clinical study according to which lamotrigine or gabapentin was better tolerated than carbamazepine in patients with geriatric epilepsy. 593 patients of age 65 years of age with newly diagnosed epilepsy, who were untreated, treated only acutely, or treated but at subtherapeutic levels, were included in the study. Exclusion criteria included life expectancy less than 12 months, conditions that would affect the response to treatment, progressive neurologic disease, severe psychiatric disorders, current alcoholism, illicit drug use, and a history of noncompliance.


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