Trimethoprim reduced dysuria in women with symptoms of urinary tract infection but negative urine dipstick test results

January 2006
ACP Journal Club;Jan/Feb2006, Vol. 144 Issue 1, p1
Academic Journal
This article reports on a clinical trial conducted to study the efficacy of trimethoprim in reducing dysuria in women with symptoms of urinary tract infection. 66 women who were 16 to 50 years of age and presented with a history of dysuria and frequency and had a negative dipstick test for both leukocytes and nitrates. 26 women were allocated to trimethoprim, 300 mg, for 3 days, and 33 were allocated to placebo. Among the 48 women who reported dysuria on day 1, fewer women in the trimethoprim group than in the placebo group still had dysuria on day 3 and day 7.


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