On bias and transparency in the development of influential recommendations

Laupacis, Andreas
January 2006
CMAJ: Canadian Medical Association Journal;1/31/2006, Vol. 174 Issue 3, p335
Academic Journal
The article looks at the potential for bias that exists in the Canadian Common Drug Review (CDR) process and contrasts this to the development of the Canadian Diabetes Association guidelines. The many potential sources of bias in the clinical literature are presented. The article then provides information on the standard methodology the CDR uses to perform a detailed independent systematic review of the available literature.


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