TITLE

The role of the Coombs test in evaluating hemolysis in adults

AUTHOR(S)
Zarandona, J. Manuel; Yazer, Mark H.
PUB. DATE
January 2006
SOURCE
CMAJ: Canadian Medical Association Journal;1/31/2006, Vol. 174 Issue 3, p305
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
This article presents a case study on the role of the Coombs test in evaluating hemolysis in adults. Coombs first described the antiglobulin test in 1945. It was conducted to detect either erythrocyte-directed immunoglobulin G (IgG) or complement coating on the surface of circulating erythrocytes. It is sufficiently large for the antihuman globulin reagent to cause agglutination of erythrocytes that are coated with IgG or complement.
ACCESSION #
19482715

 

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