TITLE

Clinical evaluation of an instrument to measure carbon dioxide tension at the oxygenator gas outlet in cardiopulmonary bypass

AUTHOR(S)
Kristiansen, Frode; Høgetveit, Jan Olav; Pedersen, Thore H
PUB. DATE
January 2006
SOURCE
Perfusion;Jan2006, Vol. 21 Issue 1, p21
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
This paper presents the clinical testing of a new capnograph designed to measure the carbon dioxide tension at the oxygenator exhaust outlet in cardiopulmonary bypass (CPB). During CPB, there is a need for reliable, accurate and instant estimates of the arterial blood CO2 tension (PaCO2) in the patient. Currently, the standard practice for measuring PaCO2 involves the manual collection of intermittent blood samples, followed by a separate analysis performed by a blood gas analyser. Probes for inline blood gas measurement exist, but they are expensive and, thus, unsuitable for routine use. A well-known method is to measure PexCO2, ie, the partial pressure of CO2 in the exhaust gas output from the oxygenator and use this as an indirect estimate for PaCO2. Based on a commercially available CO2 sensor circuit board, a laminar flow capnograph was developed. A standard sample line with integrated water trap was connected to the oxygenator exhaust port. Fifty patients were divided into six different groups with respect to oxygenator type and temperature range. Both arterial and venous blood gas samples were drawn from the CPB circuit at various temperatures. Alfa-stat corrected pCO2 values were obtained by running a linear regression for each group based on the arterial temperature and then correcting the PexCO2 accordingly. The accuracy of the six groups was found to be (±SD): ±4.3, ±4.8, ±5.7, ±1.0, ±3.7 and ±2.1%. These results suggest that oxygenator exhaust capnography is a simple, inexpensive and reliable method of estimating the PaCO2 in both adult and pediatric patients at all relevant temperatures.
ACCESSION #
19417365

 

Related Articles

  • Development of an instrument to indirectly monitor arterial pCO2 during cardiopulmonary bypass. Høgetveit, Jan Olav; Kristiansen, Frode; Pedersen, Thore H // Perfusion;Jan2006, Vol. 21 Issue 1, p13 

    Arterial blood carbon dioxide tension (PaCO2) during cardiopulmonary bypass (CBP) is important to the conduct of perfusion with alpha-stat or pH-stat strategy. Temperature changes during CBP complicate any attempts to monitor carbon dioxide tension in the exhaust outlet of an oxygenator (PexCO2)...

  • In New Study EMMA Capnograph has Comparable Accuracy to Side stream Capnography against Gold-Standar.  // Medical Buyer;11/19/2015, p1 

    The article reports on a study that compared the end tidal carbon dioxide values from the Masimo EMMA capnograph and a conventional side stream capnography device to the gold-standard carbon dioxide measurement arterial blood gas.

  • End-Tidal and Arterial Carbon Dioxide Measurements Correlate Across All Levels of Physiologic Dead Space. McSwain, S. David; Hamel, Donna S.; Smith, P. Brian; Gentile, Michael A.; Srinivasan, Saumini; Meliones, Jon N.; Cheifetz, Ira M. // Respiratory Care;Mar2010, Vol. 55 Issue 3, p288 

    BACKGROUND: End-tidal carbon dioxide (PETCO2) is a surrogate, noninvasive measurement of arterial carbon dioxide (PaCO2), but the clinical applicability of PETCO2 in the intensive care unit remains unclear. Available research on the relationship between PETCO2 and PaCO2 has not taken a detailed...

  • Capnographic Monitoring Reduces the Incidence of Arterial Oxygen Desaturation and Hypoxemia During Propofol Sedation for Colonoscopy: A Randomized, Controlled Study (ColoCap Study). Beitz, Analena; Riphaus, Andrea; Meining, Alexander; Kronshage, Tim; Geist, Christoph; Wagenpfeil, Stefan; Weber, Andreas; Jung, Andreas; Bajbouj, Monther; Pox, Christian; Schneider, Gerhard; Schmid, Roland M; Wehrmann, Till; Delius, Stefan von // American Journal of Gastroenterology;Aug2012, Vol. 107 Issue 8, p1205 

    OBJECTIVES:The aim of this randomized study was to determine whether intervention based on additional capnographic monitoring reduces the incidence of arterial oxygen desaturation during propofol sedation for colonoscopy.METHODS:Patients (American Society of Anesthesiologists classification...

  • Dead space. Lucangelo, U.; Blanch, L. // Intensive Care Medicine;Apr2004, Vol. 30 Issue 4, p576 

    Looks into the concept of dead space. Homogeneity between ventilation and perfusion; Use of capnography to measure partial pressures or fractions during the breathing cycle; Measurement of dead space using CO2.

  • Comparison of three different methods to confirm tracheal tube placement in emergency intubation. Grmec, Štefek // Intensive Care Medicine;Jun2002, Vol. 28 Issue 6, p701 

    Objectives Verification of endotracheal tube placement is of vital importance, since unrecognized esophageal intubation can be rapidly fatal (death, brain damage).The aim of our study was to compare three different methods for immediate confirmation of tube placement: auscultation, capnometry...

  • Reference values for volumetric capnography-derived non-invasive parameters in healthy individuals. Tusman, Gerardo; Gogniat, Emiliano; Bohm, Stephan; Scandurra, Adriana; Suarez-Sipmann, Fernando; Torroba, Agustin; Casella, Federico; Giannasi, Sergio; Roman, Eduardo // Journal of Clinical Monitoring & Computing;Jun2013, Vol. 27 Issue 3, p281 

    The aim of this study was to determine typical values for non-invasive volumetric capnography (VCap) parameters for healthy volunteers and anesthetized individuals. VCap was obtained by a capnograph connected to the airway opening. We prospectively studied 33 healthy volunteers 32 ± 6 years...

  • Assessment and confirmation of tracheal intubation when capnography fails: a novel use for an USB camera. Karippacheril, John; Umesh, Goneppanavar; Nanda, Shetty // Journal of Clinical Monitoring & Computing;Oct2013, Vol. 27 Issue 5, p531 

    A 62 year old male with a right pyriform fossa lesion extending to the right arytenoid and obscuring the glottic inlet was planned for laser assisted excision. Direct laryngoscopic assessment after topicalization of the airway, showed a Cormack Lehane grade 3 view. We report a case where, in the...

  • Capnography during cardiopulmonary resuscitation: Current evidence and future directions. Kodali, Bhavani Shankar; Urman, Richard D. // Journal of Emergencies, Trauma & Shock;Oct-Dec2014, Vol. 7 Issue 4, p332 

    Capnography continues to be an important tool in measuring expired carbon dioxide (CO2). Most recent Advanced Cardiac Life Support (ACLS) guidelines now recommend using capnography to ascertain the effectiveness of chest compressions and duration of cardiopulmonary resuscitation (CPR). Based on...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics