TITLE

Adjunctive Diagnostic Value of Targeted Electrical Impedance Imaging to Conventional Methods in the Evaluation of Breast Lesions

AUTHOR(S)
Szabó, B. K.; Saracco, A.; Wilczek, B.; Boné, B.; Aspelin, P.
PUB. DATE
December 2005
SOURCE
Acta Radiologica;Dec2005, Vol. 46 Issue 8, p782
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Purpose: To determine the diagnostic accuracy of targeted electrical impedance imaging in characterizing breast lesions, and to evaluate whether lesion size, depth and histopathology affect the diagnosis. Material and Methods: A total of 137 women with 145 lesions (79 malignant and 66 benign) found by palpation or mammography were prospectively enrolled in this study. The patients were examined by means of clinical breast examination, mammography, ultrasonography, and electrical impedance imaging with TransScan TS2000. A level of suspicion (LOS) post-processing algorithm (v2.67) was used for TS2000 lesion assessment. Imaging findings were correlated with cytologic ( n = 54) and histologic diagnoses ( n = 91). Patients with benign lesions were followed up for a mean of 36 months. Results: TS2000 showed a high sensitivity (86%) which did not differ significantly from that of mammography (87%) and ultrasonography (US) (75%). The specificity of TS2000 (49%) was significantly lower compared to mammography (97%, P z = 0.68), as measured by the area under the ROC curve, was significantly lower than for mammography (A z = 0.93, P < 0.0001) and for US (A z = 0.91, P < 0.0001). When using TS2000 in addition to mammography and US (A z = 0.86), a significant impairment was found ( P = 0.0003). Conclusion: The role of targeted electrical impedance imaging as an adjunct to mammography and ultrasonography in the diagnosis of breast lesions is not justified by the result of this study.
ACCESSION #
19378022

 

Related Articles

  • INVASIVE CYSTIC HYPERSECRETORY DUCTAL CARCINOMA of THE BREAST. Kamer, Erdinç; Ünalp, Haluk Recai; Akgüner, Taner; Yiğit, Seyran; Önal, Mehmet Ali // Meme Sagligi Dergisi / Journal of Breast Health;2008, Vol. 4 Issue 2, p115 

    The cystic hypersecretory ductal carcinoma of the breast are rare. These lesions of the breast are usually low-graded, but also can be observed as high-graded or invasive carcinomas. A 40-year-old woman admitted with a 3-month history of a mass in her left breast. Examination revealed a 2 cm...

  • Breast cancer detection using automated whole breast ultrasound and mammography in radiographically dense breasts. Kelly, Kevin M.; Dean, Judy; Comulada, W. Scott; Sung-Jae Lee // European Radiology;Mar2010, Vol. 20 Issue 3, p734 

    Mammography, the standard method of breast cancer screening, misses many cancers, especially in dense-breasted women. We compared the performance and diagnostic yield of mammography alone versus an automated whole breast ultrasound (AWBU) plus mammography in women with dense breasts and/or at...

  • Influence of additional breast ultrasound on cancer detection in a cohort study for quality assurance in breast diagnosis—analysis of 102,577 diagnostic procedures. Schaefer, Fritz K. W.; Waldmann, A.; Katalinic, A.; Wefelnberg, C.; Heller, M.; Jonat, W.; Schreer, I. // European Radiology;May2010, Vol. 20 Issue 5, p1085 

    To determine the value of a breast ultrasound (US) examination in addition to mammography in cases of American College of Radiology (ACR) tissue pattern III and IV in symptomatic women and women at risk. A prospective cohort was initiated between 2001 and 2005 with a total of 59,514 patients and...

  • Electrical impedance scanning in breast cancer imaging: correlation with mammographic and histologic diagnosis. Martín, Gonzalo; Martín, Rocío; Brieva, María; Santamaría, Luis // European Radiology;Jun2002, Vol. 12 Issue 6, p1471 

    This work was addressed to study correlations between histopathology of breast malignancy and variations in depth, intensity, multiplicity, and simultaneous capacitance–conductance features of electrical impedance scanning (EIS), in cases presenting mammographic findings. The EIS was...

  • Chapter 29: VIEWS FROM A MAMMOGRAPHY TECHNOLOGIST. Berman, Joel // Comprehensive Breast Care;2000, p238 

    This chapter provides tips for mammogram examination of women with breast cancer in the U.S. Schedule between 1-2 weeks after your period when your breasts are less tender or when you know your breasts are less tender. Comparing previous mammograms, besides being required as part of a facility's...

  • HER-2/NEU ONCOPROTEIN  // Davis's Comprehensive Handbook of Laboratory & Diagnostic Tests ;Jan2006, p757 

    Breast cancer is the most common newly diagnosed cancer in American women. It is the second leading cause of cancer-related death. The presence of abnormal amounts of a protein called human epidermal growth factor receptor 2 (HER-2/neu oncoprotein) is helpful in establishing histologic evidence...

  • Role of combined BI-RADS assessment using mammography and sonography for evaluation of incidental hypermetabolic lesions in the breast on 18F-FDG PET-CT. Lim, Soyeoun; Lee, Eun Hye; Park, Jung Mi; Chang, Yon-Woo; Kim, Hyung Hwan; Jeong, Sun Hye // Acta Radiologica;Dec2013, Vol. 54 Issue 10, p1117 

    The article presents a study which examines the evaluation of incidental hypermetabolic lesions in the breast on 18F-FDG PET-CT using combined Breast Imaging-Reporting and Data System (BI-RADS) assessment with mammography and sonography. It is inferred that 0.6 percent of 7,594 women who...

  • Interventions to Promote Repeat Breast Cancer Screening With Mammography: A Systematic Review and Meta-Analysis. Vernon, Sally W.; McQueen, Amy; Tiro, Jasmin A.; Del Junco, Deborah J. // JNCI: Journal of the National Cancer Institute;Jul2010, Vol. 102 Issue 14, p1023 

    Background: Various interventions to promote repeat use of mammography have been evaluated, but the efficacy of such interventions is not well understood.

  • Projecting mammographic screens. Parr, N.; Boyages, John; Taylor, R.; Anura, P.; Callaghan, Terry // Journal of Medical Screening;Sep2000, Vol. 7 Issue 3, p146 

    Objective The purpose of mammographic screening is to reduce mortality from breast cancer. This study describes a method for projecting the number of screens to be performed by a mammographic screening programme, and applies this method in the context of New South Wales, Australia. Method The...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics