Evaluation of Buprenorphine CEDIA Assay versus GC-MS and ELISA using Urine Samples from Patients in Substitution Treatment

Böttcher, Michael; Beck, Olof
November 2005
Journal of Analytical Toxicology;Nov/Dec2005, Vol. 29 Issue 8, p769
Academic Journal
The study evaluates an immunochemical test based on cloned enzyme-donor immunoassay (CEDIA) technology for the use in clinical urine drug testing. The method was compared with an existing enzyme-linked immunosorbent immunoassay method and a gas chromatography-mass spectrometry method on urine specimens from patients in heroin substitution treatment. It concludes that the buprenorphine CEDIA assay is suitable for application in high-volume screening of buprenorphine for urine drug testing.


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