TITLE

PANETH CELLS: THEIR ROLE IN INNATE IMMUNITY AND INFLAMMATIORY DISEASE

AUTHOR(S)
Elphick, D. A.; Mahida, Y. R.
PUB. DATE
December 2005
SOURCE
Gut;Dec2005, Vol. 54 Issue 12, p1802
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
In this article, we discuss the current understanding of how the intestinal mucosa may exert control over luminal bacteria, and how intestinal inflammation could ensue when this control is lost. We shall review research showing how Paneth cells, and evolutionarily conserved innate immune mechanisms, are emerging as key mediators of intestinal mucosal defence.
ACCESSION #
19160206

 

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