Birth size and colorectal cancer risk: a prospective population based study

Nisen, T. I. L.; Romundstad, P. R.; Troisi, R.; Potischman, N.; Vatten, L. J.
December 2005
Gut;Dec2005, Vol. 54 Issue 12, p1728
Academic Journal
Objective: To study whether birth size influences colorectal cancer risk in adulthood. Design: A cohort of Norwegian men and women identified from midwives' birth records with long term cancer follow up through the Norwegian Cancer Registry. Setting: St Olav's University Hospital, Trondheim, Norway. Participants: 16 016 women and 19 681 men born between 1920 and 1958 and alive in 1960. Outcome measures: Incidence rate ratios (RRs) for colorectal cancer with 95% confidence intervals (CIs) and two sided p values for trend across categories of birth dimensions. Results: Men whose birth length was less than 51 cm had a nearly twofold higher risk of colorectal cancer (RR 1.9(95% CI 1.0-3.7)) compared with men who were 53 cm or more, after adjustment for birth cohort, maternal age at childbearing, length of gestation, gestational hypertension or pre-eclampsia, birth order, maternal height, and indicators of maternal socioeconomic status. The association displayed a linear trend across categories of birth length (Ptrend = 0.03). Among men, similar associations were found for birth weight and head circumference, but for women there was no association between any of these birth dimensions and risk of colorectal cancer. Conclusion: The results suggest that among men, but not women, being relatively short at birth is associated with increased risk of colorectal cancer in adulthood, indicating that intrauterine growth could be important for colorectal carcinogenesis.


Related Articles

  • Birth Weight of Healthy Newborns in Zagreb Area, Croatia. Kolčić, Ivana; Polašek, Ozren; Pfeifer, Dina; Smolej-Narančić, Nina; Ilijić, Marcela; Bljajić, Danko; Biloglav, Zrinka; Ivanišević, Marina; Delmiš, Josip // Collegium Antropologicum;Jun2005, Vol. 29 Issue 1, p257 

    The aim of this study was to assess birth weight of healthy newborns from the City of Zagreb and Zagreb County, Croatia. Birth weights of healthy newborns, born at the Department of Obstetrics and Gynecology, University Hospital Center »Zagreb« in the year 2001, were included into...

  • Maternal Risk Factors Of Low Birth Weight In Chandigarh India. Sharma, Munesh K.; Kumar, Dinesh; Huria, Anju; Gupta, Pratiksha // Internet Journal of Health;2009, Vol. 9 Issue 1, p15 

    Objectives: To investigate risk factors of Low Birth Weight. Setting: Govt. Medical College and Hospital, Chandigarh. Participants: 193neonates delivered in the health facility. Statistical Analysis: Normal test of proportions. Results: The overall proportion of LBW was 23.8%. Proportion of LBW...

  • prenatal vitamins & infant birth weight. Lofshult, Diane // IDEA Fitness Journal;Jun2007, Vol. 4 Issue 6, p83 

    The article reports on a study which examined the relation between prenatal vitamins and infant birth weight. The study which appeared in the "Archives of Pediatrics and Adolescent Medicine" has found that the infants born to women with pre-natal vitamin supplementation were heavier. The impact...

  • Monk Birth Announcement.  // Stonewall County Courier (Aspermont, TX);8/31/2006, Vol. 20 Issue 43, p4 

    The article reports on the birth of Brylie Monk. The announcement was made by Tahle Monk, who is Brylie Monk's older sister. Brylie was born on July 19, 2006 in Lubbock, Texas. She weighed seven pounds, nine ozs. and 21 inches long. Her parents are Bobbie Sue and Ryan Monk. Her maternal...

  • Socio-Economic and Nutritional Determinants of Low Birth Weight in India. Kader, Manzur; Perera, Nirmala K. P. // North American Journal of Medical Sciences;Jul2014, Vol. 6 Issue 7, p302 

    Background: Low birth weight (LBW) is an important risk factor for childhood morbidity and mortality, consequently an important public health concern. Aim: This study aims to identify signifi cant socio-economic and nutritional determinants associated with LBW in India. Materials and Methods:...

  • Predictability of Fetal Birth Weight from Measurement of Fetal Thigh Circumference by Two-dimensional Ultrasound: A Prospective Study. Sanyal, Poushali; Ghosh, Tarun Kumar; Dasgupta, Shyamal; Karim, Rezaul; Mukherjee, Amitava; Das, Anita // Journal of South Asian Federation of Obstetrics & Gynecology;Jan-Apr2012, Vol. 4 Issue 1, p35 

    Objective: The aim of this study was to compare the predictability of the Vintzileos' formula with the Hadlock's formula in estimating the fetal weight nearest to the actual birth weight. Methods: It was a prospective observational study conducted with 138 antenatal mothers with single viable...

  • SECULAR TRENDS IN ANTHROPOMETRICAL MEASUREMENTS OF INFANTS IN LATVIA. Oginska, Anita; Vētra, Jānis; Pilmane, Māra // Papers on Anthropology;2009, Vol. 18, p273 

    The aim of the presented study was to find secular trends for newborns' height and weight at birth dynamics over the century in Latvia. Over the last 79 years six research papers about newborns in Riga -- the capital of Latvia -- have been published. The results of those different researches...

  • Gestational Age-specific Centile Charts for Anthropometry at Birth for South Indian Infants. Kandraju, Hemasree; Agrawal, Shilpa; Geetha, K.; Sujatha, Lakshmi; Subramanian, Sreeram; Murki, Srinivas // Indian Pediatrics;Mar2012, Vol. 49 Issue 3, p199 

    Objective: To construct centile charts for birth weight, length and head circumference for infants born from 24 to 42 weeks of gestation and to compare with the other national and international growth charts. Study design: Observational descriptive study. Subjects: All consecutively live born...

  • Relation of Birth Weight to Different Maternal Factors. Maity, Manosij // Australasian Medical Journal;Aug2010, Vol. 3 Issue 8, p535 

    Introduction Low birth weight is a significant health problem for the family and society at large. UNICEF/WHO estimated the incidence of low birth weight in India as 30%(2008). The questions arising were; what is the prevalence of low birth weight in hospital set up at Agartala? What factors are...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics