TITLE

Diagnosis of small bowel Crohn's disease: a prospective comparison of capsule endoscopy with magnetic resonance imaging and fluoroscopic enteroclysis

AUTHOR(S)
Albert, J. G.; Martiny, F.; Krummenerl, A.; Stock, K.; Leβke, J.; Göbel, C. M.; Lotterer, E.; Nietsch, H. H.; Behrmann, C.; Fleig, W. E.
PUB. DATE
December 2005
SOURCE
Gut;Dec2005, Vol. 54 Issue 12, p1721
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Background and aims: The diagnostic yield of capsule endoscopy (CE) compared with magnetic resonance imaging (MRI) in small bowel Crohn's disease is not well established. We prospectively investigated CE, MRI, and double contrast Huoroscopy in patients with suspected small bowel Crohn's disease. Methods: Fifty two consecutive patients (39 females, 13 males) were investigated by MRI, fluoroscopy and- if bowel obstruction could be excluded-by CE. In 25, Crohn's disease was newly suspected while the diagnosis of Crohn's disease (non-small bowel) had been previously established in 27. Results: Small bowel Crohn's disease was diagnosed in 41 of 52 patients (79%). CE was not accomplished in 14 patients due to bowel strictures. Of the remaining 27 patients, CE, MRI, and fluoroscopy detected small bowel Crohn's disease in 25 (93%), 21(78%), and 7 (of 21; 33%) cases, respectively. CE was the only diagnostic tool in four patients. CE was slightly more sensitive than MRI (12 v 10 of 13 in suspected Crohn's disease and 13 v 11 of 14 in established Crohn's disease). MRI detected inflammatory conglomerates and enteric fistulae in three and two cases, respectively. Conclusion: CE and MRI are complementary methods for diagnosing small bowel Crohn's disease. CE is capable of detecting limited mucosal lesions that may be missed by MRI, but awareness of bowel obstruction is mandatory. In contrast, MRI is helpful in identifying transmural Crohn's disease and extraluminal lesions, and may exclude strictures.
ACCESSION #
19160193

 

Related Articles

  • Back to the drawing-board.  // Gut;Mar2007, Vol. 56 Issue 3, p416 

    The article discusses the study focused on the combination use of immunosuppression, selective magnetic resonance imaging (MRI) scanning and examination to rule out Fistulating Crohn's disease. The disease is a therapeutic challenge where treatment agents like infliximab held great promise but...

  • Bowel magnetic resonance imaging of pediatric patients with oral mannitol. Borthne, Arne S.; Abdelnoor, Michael; Rugtveit, Jarle; Perminow, Göri; Reiseter, Tor; Kløw, Nils-Einar // European Radiology;Jan2006, Vol. 16 Issue 1, p207 

    The purpose of this study was to assess the sensitivity, specificity, and diagnostic accuracy of magnetic resonance imaging (MRI) in pediatric patients with clinical suspicion of inflammatory bowel disease (IBD) by comparing MRI and ultrasound (US) to endoscopy, the gold standard. A median...

  • A prospective randomized comparison between two MRI studies of the small bowel in Crohn’s disease, the oral contrast method and MR enteroclysis. Negaard, Anne; Paulsen, Vemund; Sandvik, Leiv; Berstad, Audun Elnaes; Borthne, Arne; Try, Kirsti; Lygren, Idar; Storaas, Tryggve; Klow, Nils-Einar // European Radiology;Sep2007, Vol. 17 Issue 9, p2294 

    The aim was to compare bowel distension and diagnostic properties of magnetic resonance imaging of the small bowel with oral contrast (MRI per OS) with magnetic resonance enteroclysis (MRE). Forty patients with suspected Crohn’s disease (CD) were examined with both MRI methods. MRI per OS...

  • Crohn disease of the small bowel: MR enteroclysis versus conventional enteroclysis. Masselli, G.; Vecchioli, A.; Gualdi, G. F. // Abdominal Imaging;Jul2006, Vol. 31 Issue 4, p400 

    Enteroclysis has been suggested as the technique of choice for the evaluation of Crohn disease of the small intestine. Adequate distention of the entire small bowel with barium suspension allows the radiologic demonstration of mucosal abnormalities and provides functional information by defining...

  • A Prospective Comparison Study of MRI versus Small Bowel Follow-Through in Recurrent Crohn's Disease. Bernstein, Charles N.; Greenberg, Howard; Boult, Ian; Chubey, Shirley; Leblanc, Corrine; Ryner, Lawrence // American Journal of Gastroenterology;Nov2005, Vol. 100 Issue 11, p2493 

    BACKGROUND: We aimed to determine the utility of magnetic resonance imaging (MRI) compared with small bowel follow-through (SBFT) in the assessment of known Crohn's disease. METHODS: Subjects, over age 18 yr who were to undergo SBFT investigations to assess for complications or extent of Crohn's...

  • Ulcerative colitis: value of MR imaging. Maccioni, F.; Colaiacomo, M. C.; Parlanti, S. // Abdominal Imaging;Sep/Oct2005, Vol. 30 Issue 5, p584 

    Recent technologic advances have greatly improved the quality of abdominal magnetic resonance imaging (MRI) by allowing the identification of abnormalities in inflammatory bowel disease. Thus far, the role of MRI has been extensively investigated in Crohn disease (CD) and, to a minor extent, in...

  • Evaluation of Crohn's disease activity: Initial validation of a magnetic resonance enterography global score (MEGS) against faecal calprotectin. Makanyanga, Jesica; Pendsé, Doug; Dikaios, Nikolaos; Bloom, Stuart; McCartney, Sara; Helbren, Emma; Atkins, Elaine; Cuthbertson, Terry; Punwani, Shonit; Forbes, Alastair; Halligan, Steve; Taylor, Stuart // European Radiology;Feb2014, Vol. 24 Issue 2, p277 

    Objectives: To develop an MRI enterography global score (MEGS) of Crohn's disease (CD) activity compared with a reference standard of faecal calprotectin (fC), C-reactive protein (CRP) and Harvey-Bradshaw index (HBI). Methods: Calprotectin, CRP and HBI were prospectively recorded for 71 patients...

  • Small bowel imaging- a rapidly changing field and a challenge to radiology. Maglinte, Dean D. T. // European Radiology;May2006, Vol. 16 Issue 5, p967 

    There was a time when the small bowel follow-through (SBFT) was the primary method of diagnosing diseases of the small intestine. Enteroclysis was reinvented in the 70's and with the SBFT remained the dominant methods of investigating the mesenteric small intestine to the late 90's. Since the...

  • NEW DIAGNOSTIC IMAGING TOOLS FOR INFLAMMATORY BOWEL DISEASE. Mackaiski, B. A.; Bernstein, C. N. // Gut;May2006, Vol. 55 Issue 5, p733 

    The article focuses on the advancement of diagnostic imaging systems for inflammatory bowel disease. The wireless capsule endoscopy enables a painless and radiation free examination. The magnetic resonance imaging provides information about extraintestinal intra-abdominal structures. The...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sign out of this library

Other Topics