Expression of p53 and Apoptosis in Discoid Lupus Erythematosus

Weinreb, David B.; Desman, Garrett T.
December 2005
Croatian Medical Journal;2005, Vol. 46 Issue 6, p998
Academic Journal
The article comments on a discussion regarding p53 gene expression and apoptosis in discoid lupus erythematosus (DLE) by G. Zamolo et al published in the 2005 issue of "Croatia Medical Journal." It was inferred that the form of p53 in neoplastic tissues, including skin lesions damaged by UVB radiation, was non-functional, but stabilized mutant. It also speculated that the p53 expression may result from polyoma virus infection in DLE.


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