Palmoplantar keratoderma ("tripe palms") associated with primary pulmonary adenocarcinoma

Patel, A.; Teixeira, F.; Redington, A. E.
November 2005
Thorax;Nov2005, Vol. 60 Issue 11, p976
Academic Journal
journal article
The article presents a case of palmoplantar keratoderma associated with primary pulmonary adenocarcinoma in a 61 year old woman. The woman was investigated for a 12 month history of progressive thickening of the skin of her palms and soles. She had also complained of diarrhoea, exertional breathlessness and cough, and weight loss. There was no relevant past medical history or family history, but she had a 45 pack year history of cigarette smoking. Physical examination revealed diffuse hyperkeratosis of the palms and soles, digital clubbing, and right sided chest signs. Her chest radiograph and thoracic CT scan showed a mass in the right upper lobe. The keratoderma was managed initially with 10% salicylic acid in Vaseline with some response. As the tumour was inoperable on the grounds of lung function, the patient received systemic chemotherapy.


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