Endoscopic ultrasound-guided fine-needle aspiration biopsy (EUS-FNAB): past, present, and future

Yamao, Kenji; Sawaki, Akira; Mizuno, Nobumasa; Shimizu, Yasuhiro; Yatabe, Yasushi; Koshikawa, Takashi
November 2005
Journal of Gastroenterology;Nov2005, Vol. 40 Issue 11, p1013
Academic Journal
Endoscopic ultrasound (EUS) is a combination of endoscopy and intraluminal ultrasonography. EUS also enables ultrasonographic images of high resolution to be obtained. However, whether a lesion is malignant or benign cannot be diagnosed solely from the findings of EUS. Endoscopic ultrasound-guided fine-needle aspiration biopsy (EUS-FNAB) was developed to enhance the diagnostic capabilities of EUS by providing additional pathological findings. Though more than 10 years have passed since EUS-FNAB was first used for pancreatic disease, EUS FNAB has not been widely accepted in Japan. This may be due to the technical difficulties, relatively low sensitivity for the detection of malignancies, and Japanese gastroenterologists' and surgeons' inherent conservative way of thinking. We describe here a short history of EUS-FNAB, with details of technical tips, current indications and contraindications, diagnostic accuracy, and complications. The clinical utility of EUS-FNAB has been gradually understood and EUS-FNAB procedures have been increasing in number in Japan. So in the near future, EUS followed by EUS-FNAB will be routinely performed in the same manner as gastrointestinal endoscopy, followed by biopsy under direct vision. Also, therapeutic EUS procedures, such as EUS-guided celiac plexus neurolysis, pancreatic tumor ablation, drainage of pancreatic pseudocysts, and the development of an anastomosis may become feasible as less invasive and safer techniques than those used at present.


Related Articles

  • Evaluation of endoscopic ultrasonography in colorectal villous lesions. Konishi, Kazuo; Akita, Yasushi; Kaneko, Kazuhiro; Kurahashi, Toshionori; Yamamomoto, Taikan; Kusayanagi, Satoshi; Yoshikawa, Nozomi; Miyasaka, Nobuo; Tajiri, Hisao; Mitamura, Keiji // International Journal of Colorectal Disease;Jan2003, Vol. 18 Issue 1, p19 

    Background and aims. The choice of therapeutic procedure for colorectal neoplasias depends largely on the depth of tumor invasion. This study examined the value of endoscopic ultrasonography (EUS) in determining whether local resection is applicable for colorectal villous lesions. Materials and...

  • Comparing endobronchial ultrasound-guided fine needle aspiration specimens with and without rapid on-site evaluation. Monaco, Sara E.; Pantanowitz, Liron; Khalbuss, Walid E.; Carruth Griffin, Adrienne; Ende Schwartz, Lauren; Baloch, Zubair // CytoJournal;2012, Vol. 9 Issue 1, p1 

    No abstract available.

  • Intravascular Ultrasonography: Can It Now Document Plaque and Artery Morphology or Virtual Histology? Reid, Donald B. // Vascular;Nov2005 Supplement, Vol. 13, pS77 

    The article examines whether intravascular ultrasonography (IVUS) can document plaque and artery morphology or virtual histology. Background information on IVUS is offered. A discussion on the role of virtual histology IVUS in determining the nature and composition of arteriosclerotic plaque is...

  • Intravascular Ultrasound: Value of Electronic and Mechanical Devices for Quantifying Mild to Moderate Atherosclerosis. Duda, Stephan H.; Wehrmann, Manfred; Erdtmann, Bernd; Huppert, Peter E.; Claussen, Claus D. // Angiology;Jul1994, Vol. 45 Issue 7, p597 

    To define the accuracy of electronic and mechanical ultrasound (US) devices for determining the thickness of intima and media, 32 fresh normal and atherosclerotic human femoral arteries were obtained at necropsy. The samples were imaged with a 64-element array and a mechanically rotating US...

  • Endoscopic ultrasound guided fine needle aspiration of non-pancreatic lesions: an institutional experience. Anand, Dipti; Barroeta, Julieta E.; Gupta, Prabodh K.; Kochman, Michael; Baloch, Zubair W. // Journal of Clinical Pathology;Nov2007, Vol. 60 Issue 11, p1254 

    Background: Endoscopic ultrasound guided fine needle aspiration biopsy (EUS-FNA) has proven to be an effective diagnostic modality for the detection and staging of pancreatic malignancies. In recent years EUS-FNA has also been used to diagnose lesions of non-pancreatic sites such as structures...

  • Impact of Endoscopic Ultrasound on the Management and Outcome of Pancreatic Carcinoma. Erickson, Richard A.; Garza, Aldo A. // American Journal of Gastroenterology;Sep2000, Vol. 95 Issue 9, p2248 

    OBJECTIVE: Although endoscopic ultrasound and endoscopic ultrasound-guided fine needle aspiration have been shown lo aid in the diagnosis and staging of pancreatic carcinoma, whether the general use of these new techniques impacts the overall management and survival of pancreatic cancer, is less...

  • Endoscopic Ultrasound Cannot Determine Suitability for Esophagectomy After Aggressive Chemoradiotherapy for Esophageal Cancer. Zuccaro Jr., Gregory; Rice, Thomas W.; Goldblum, John; Medendorp, Sharon V.; Becker, Mark; Pimentel, Ronnie; Gitlin, Laura; Adelstein, David J. // American Journal of Gastroenterology;Apr1999, Vol. 94 Issue 4, p906 

    OBJECTIVE: Endoscopic ultrasound (EUS) provides important information in the initial staging of patients with esophageal cancer. With recent modifications in chemoradiotherapy protocols, a significant number of patients have no residual tumor at esophagectomy. The high surgical morbidity and...

  • Intravenous Intravascular Ultrasound Using the AcuNav Ultrasound Catheter for Guiding Recanalization of Aortoiliac Chronic Total Occlusions. Hishikari, Keiichi; Hikita, Hiroyuki; Sugiyama, Tomoyo; Oumi, Tetsuo; Kimura, Shigeki; Takahashi, Atsushi; Isobe, Mitsuaki // Journal of Endovascular Therapy (Sage Publications Inc.);Apr2015, Vol. 22 Issue 2, p269 

    The article focuses on the use of intravascular ultrasound (IVUS) imaging for the recanalization of chronic total occlusions (CTOs) in peripheral arteries. Topics discussed include the AcuNav intravascular ultrasound catheter used for intracardiac echocardiography, the use of new-generation IVUS...

  • Early esophageal carcinoma: endoscopic ultrasonography using the sonoprobe. Kawano, T.; Ohshima, M.; Iwai, T. // Abdominal Imaging;Jul/Aug2003, Vol. 28 Issue 4, p0477 

    Background: Almost all cases of superficial esophageal carcinoma are curable by endoscopic mucosal resection (EMR), but a precise diagnosis of the depth of tumor invasion is necessary to assess the indication for EMR. Although endoscopy has a high rate of accuracy for diagnosing the depth of...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics