Biochemistry -- Trace Elements

McGlannan, Frances; Maugh, II, Thomas H.
April 1974
Journal of Learning Disabilities;Apr1974, Vol. 7 Issue 4, p210
Academic Journal
This article focuses on the effects of trace elements on humans. Scientists have for some time recognized that trace concentrations of certain elements, such as iron and zinc, are essential to human metabolism; that other elements, such as lead and cadmium, are toxic at similar concentrations; and that still others, such as selenium, can be both beneficial and toxic within a fairly narrow range of concentrations. The time may be fast approaching when evaluation of trace element concentrations will play a fundamental role in the diagnosis of illness. The detrimental effects of certain trace elements and their derivatives have become very well known. Lead and methylmercury, for example, have been shown to damage the central nervous system. Many trace elements are beneficial. At the latest count, 14 different trace elements have been identified as essential to human health. Cobalt, zinc and manganese serve as cofactors for various metabolic enzymes, and iron is an integral component of hemoglobin. Concentrations of the various elements are closely interconnected in human physiology, and there is growing evidence that at least some effects of toxic trace elements result not so much from inherent toxicity of the elements as from their interference with the function of other elements.


Related Articles

  • Growth effect on the uptake and elimination of trace metals in the abalones Haliotis. ARAI, TAKAOMI; MAEDA, MASARU; YAMAKAWA, HIROSHI; KAMATANI, AKIYOSHI; MIYAZAKI, NOBUYUKI // Fisheries Science;Oct2002, Vol. 68 Issue 5, p1094 

    ABSTRACT: In order to determine trace metal (cadmium, copper, lead, manganese and zinc) levels in muscles in relation to organism growth, abalones Haliotis at various stages from Japanese coastal regions were collected and analyzed. Concentrations of Cd and Pb, two non-essential metals, in the...

  • The Effects of Acute Submaximal Exercise on Trace Element Metabolism. Kara, Ersan // HealthMed;2011, Vol. 5 Issue 6, p1580 

    Background: Trace elements play a significant role in many physiological and biochemical events happening in body. In this study, it was aimed to investigate the effects of acute exercise done by sedentary individuals on the trace element metabolism. Objectives: The research was conducted on the...

  • Changes in Growth Performance, Metabolic Enzyme Activities, and Content of Fe, Cu, and Zn in Liver and Kidney of Tilapia ( Oreochromis niloticus ) Exposed to Dietary Pb. Linglin Fu; Huahua Du; Chengguan Jin // Biological Trace Element Research;May2009, Vol. 128 Issue 2, p176 

    Abstract  Tilapia (Oreochromis niloticus) were exposed to 0, 100, 400, and 800 μg/g concentrations of Pb in diet for 60 days, and changes in growth performance, metabolic enzyme activities, and essential trace elements (Fe, Cu, and Zn) content in liver and kidney were...

  • Iron loading and disease surveillance. Weinberg, Eugene D.; Weinberg, E D // Emerging Infectious Diseases;May/Jun99, Vol. 5 Issue 3, p346 

    Iron is an oxidant as well as a nutrient for invading microbial and neoplastic cells. Excessive iron in specific tissues and cells (iron loading) promotes development of infection, neoplasia, cardiomyopathy, arthropathy, and various endocrine and possibly neurodegenerative disorders. To contain...

  • Polymorphism in neuropeptide Y influences CSF cholesterol levels but is no major risk factor of Alzheimer’s disease. Kölsch, H.; Lütjohann, D.; Jessen, F.; Urbach, H.; von Bergmann, K.; Maier, W.; Heun, R. // Journal of Neural Transmission;Feb2006, Vol. 113 Issue 2, p231 

    Neuropeptide Y (NPY) is a neurotransmitter expressed in the central nervous system and involved in learning and memory. The NPY L7P polymorphism has been associated with altered cholesterol levels in obese patients. Since altered cholesterol metabolism is also involved in Alzheimer’s...

  • Immersion autometallographic demonstration of pathological zinc accumulation in human acute neural diseases. Zhu, Lin; Tang, Yong; Wang, Han-dong; Zhang, Zhi-yuan; Pan, Hao // Neurological Sciences;Aug2012, Vol. 33 Issue 4, p855 

    Zinc is the second most prevalent trace element in the body and is present in particularly large concentrations in the mammalian brain. In animal experiments, several lines of studies show that zinc is involved in the pathological process of ischemia, epilepsy, and mechanical head trauma....

  • STATUS OF SOME TRACE ELEMENTS IN IRAQI DIABETIC WOMEN AND ITS RELATIONSHIP WITH LIPID PROFILE. Hasan, Bushra Faris // International Journal of Science & Nature;2013, Vol. 4 Issue 1, p188 

    Trace elements are tiny molecules that play important roles in our bodies; their metabolism has been reported to alter in diabetes mellitus and might have specific roles in the pathogenesis and progress of this disease. The aim of the present study was to investigate the serum level of copper...

  • Iron transport & homeostasis mechanisms: Their role in health & disease. Nadadur, S. S.; Srirama, K.; Mudipalli, Anuradha // Indian Journal of Medical Research;Oct2008, Vol. 128 Issue 4, p533 

    Iron is an essential trace metal required by all living organisms and is toxic in excess. Nature has evolved a delicately balanced network to monitor iron entry, transport it to sites of need, and serve as a unique storage and recycling system, in the absence of an excretory system, to remove...

  • Serum chromium levels in Egyptian diabetic patients. Ahmed, Asmaa; Helal, Manal // Comparative Clinical Pathology;Dec2012, Vol. 21 Issue 6, p1373 

    A direct association between trace elements and human disease has been observed. The alteration of chromium metabolism has been observed in diabetic patients. The aim of this study was to investigate any association between serum chromium levels and diabetes mellitus in the Egyptian population....


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics