TITLE

An immediate antiepileptic drug regimen reduced short-term (2-y) recurrence of seizures more than a deferred regimen

PUB. DATE
November 2005
SOURCE
ACP Journal Club;Nov/Dec2005, Vol. 143 Issue 3, p75
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
This article presents information on a clinical study according to which an immediate antiepileptic drug (AED) regimen reduced short-term recurrence of seizures more than a deferred regimen. The study explored whether in patients with few or infrequent seizures, an immediate antiepileptic drug (AED) regimen is more effective than a deferred AED regimen for reducing recurrence of seizures. 693 patients had a seizure. 332 patients in the deferred group started on an AED regimen. AEDs were carbamazepine, valproate, phenytoin, and lamotrigine. The immediate AED regimen increased the time to first seizure and time to first tonic-clonic seizure more than the deferred regimen at 2 and 5 years.
ACCESSION #
18925754

 

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