TITLE

Review: Invasive management after unstable angina or non--ST- segment elevation MI does not reduce risk for death or MI

PUB. DATE
November 2005
SOURCE
ACP Journal Club;Nov/Dec2005, Vol. 143 Issue 3, p68
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
This article presents information on a clinical study according to which invasive management after unstable angina or non-ST-segment elevation myocardial infarction (MI) does not reduce risk for death or MI. The study explored whether in patients with unstable angina or non-ST-segment elevation myocardial infarction, initial management with an invasive strategy is better than a conservative strategy. 7 RCTs met the selection criteria. 6 RCTs were of high methodological quality. Meta-analysis of all 7 RCTs, using a random-effects model, showed no difference between strategies for all-cause mortality or the combined outcome of reinfarction or death. In patients with unstable angina or non-ST-segment elevation MI, an early invasive strategy reduces rates of fatal or nonfatal MI and rehospitalization more than a conservative strategy, but not all-cause mortality or the composite outcome of death or nonfatal MI.
ACCESSION #
18925743

 

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