A lifestyle intervention or metformin prevented or delayed the onset of the metabolic syndrome in persons at risk

November 2005
ACP Journal Club;Nov/Dec2005, Vol. 143 Issue 3, p67
Academic Journal
This article presents information on a clinical study according to which a lifestyle intervention or metformin prevented or delayed the onset of the metabolic syndrome in persons at risk. The study explored whether in persons with impaired glucose tolerance, an intensive lifestyle intervention (ILS) prevents onset or promote resolution of the metabolic syndrome. The cumulative incidence of the metabolic syndrome was lower in the ILS and metformin groups than in the placebo group. In persons with impaired glucose tolerance, an intensive lifestyle intervention or treatment with metformin plus standard lifestyle recommendations was more effective than standard lifestyle recommendations alone for preventing or delaying onset of the metabolic syndrome.


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