Endovascular and open repair did not differ for mortality rates at 2 years in abdominal aortic aneurysm: COMMENTARY

Cinà, Claudio S.; Devereaux, P.J.
November 2005
ACP Journal Club;Nov/Dec2005, Vol. 143 Issue 3, p64
Academic Journal
This article comments on a clinical study according to which endovascular and open repair did not differ for mortality rates at 2 years in abdominal aortic aneurysm. Current randomized trials of endovascular aneurysm repair (EVAR) have left many questions unanswered because of sample size, selection of surgeons, appropriateness of outcomes, and analysis. The DREAM trial had a sample size of 351 patients and only 45% power to detect a patient-important absolute risk difference of 3% in perioperative mortality. Although initial trials seemed encouraging for EVAR, all of them, including this one, have substantial design and sample size limitations.


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