TITLE

Daily corticosteroids were not better than as-needed corticosteroids in mild persistent asthma

PUB. DATE
November 2005
SOURCE
ACP Journal Club;Nov/Dec2005, Vol. 143 Issue 3, p60
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
This article presents information on a clinical study according to which daily corticosteroids were not better than as-needed corticosteroids in mild persistent asthma. This study explored that in patients with mild persistent asthma, how does intermittent, short-course corticosteroid treatment (ISCT) guided by a symptom-based action plan alone compare with ISCT plus daily treatment with either budesonide or zafirlukast for improving morning peak expiratory flow (PEF)? 225 patients 18 to 65 years of age with mild persistent asthma were studied. Change in morning PEF from the final 2 weeks of the run-in period to the final 2 weeks of the year of treatment. In patients with mild persistent asthma, intermittent, short-course corticosteroid treatment guided by a symptom-based action plan alone did not differ from daily treatment with budesonide or zafirlukast for improving morning peak expiratory flow.
ACCESSION #
18925727

 

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