Solitary Pulmonary Metastasis Presenting 20 Years After Primary Resection of Wilms Tumor

Parambil, Joseph G.; Aughenbaugh, Gregory L.; Pereira, Telma C.; Gillespie, Delmar J.; Ryu, Jay H.
November 2005
Mayo Clinic Proceedings;Nov2005, Vol. 80 Issue 11, p1514
Academic Journal
Wilms tumor is the most common renal malignancy of childhood. Relapse occurs most often within 4 years of initial diagnosis, and the most common site of metastasis is the lung. We describe a 22-year-old man who presented with hemoptysis and a solitary pulmonary lesion 20 years after primary resection of Wilms tumor. Computed tomography of the chest showed an indeterminate pulmonary mass of heterogeneous attenuation with no other intrathoracic abnormalities. Surgical resection revealed a solitary pulmonary metastasis from Wilms tumor. Further evaluation yielded no evidence of extrathoracic metastases. This case shows that late relapse in the form of a solitary pulmonary mass can occur in patients with Wilms tumor.


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