Breast Cancer-Related Lymphedema

Morrell, Rosalyn M.; Halyard, Michele Y.; Schild, Steven E.; Ali, Muna S.; Gunderson, Leonard L .; Pockaj, Barbara A.
November 2005
Mayo Clinic Proceedings;Nov2005, Vol. 80 Issue 11, p1480
Academic Journal
Every year in the United States, breast cancer is diagnosed in more than 200,000 women. Because of the prevalence of breast cancer, treatment-related sequelae are of Importance to many survivors of the disease. One such sequela is upper extremity lymphedema, which occurs when fluid accumulates in the interstitial space and causes enlargement and usually a feeling of heaviness in the limb. Axillary surgery contributes considerably to the Incidence of lymphedema, with the Incidence and severity of swelling related to the number of lymph nodes removed. Lymphedema after standard axillary lymph node dissection can occur in up to approximately 50% of patients. However, the risk of lymphedema is decreased substantially with newer sentinel lymph node sampling procedures. Adjuvant radiotherapy to the breast or lymph nodes Increases the risk of lymphedema, which has been reported in 9% to 40% of these patients. Management of lymphedema requires a multidisciplinary approach to minimize the effect on the patient's quality of life. This review presents an overview of the pathophysiology, diagnosis, prevention, and treatment of breast cancer-related lymphedema.


Related Articles

  • Breast Cancer-Related Lymphedema. MOORE, JESSICA; PAULSON, HEATHER // Naturopathic Doctor News & Review;Dec2014, Vol. 10 Issue 12, p1 

    The article discusses breast cancer-related lymphedema (BCRL), which is a growing public health issue in the U.S. as of December 2014. It claims that lymphedema (LE) affects a number of women who were treated with surgery and radiation for breast cancer. Also examined are the disease's effects...

  • Intraoperative Frozen Section of Sentinel Nodes: A Formal Decision Analysis. Chao, Celia; Abell, Troy; Martin II, Robert C. G.; McMasters, Kelly M. // American Surgeon;Mar2004, Vol. 70 Issue 3, p215 

    In the absence of data from randomized trials, a formal decision analysis was undertaken to quantify the relative value of the patients' quality of life with regard to performing intraoperative frozen section (FS) versus permanent section (PS) analysis of the sentinel lymph node (SLN) for breast...

  • Evidence-Based Analysis of Lymph Node Transfer in Postmastectomy Upper Extremity Lymphedema. Sapountzis, Stamatis; Nicoli, Fabio; Chilgar, Ram; Ciudad, Pedro // Archives of Plastic Surgery;Jul2013, Vol. 40 Issue 4, p450 

    The article presents clinical studies on lymph node transfer (LNT) in upper extremity lymphedema after breast cancer surgery, wherein 32 patients received LNT on the wrist, 32 patients on the axilla, 2 patients on the forearm and 7 patients on the axilla and elbow. Lymphedema is said to develop...

  • Research CORNER. Lacovara, Jane E. // Med-Surg Matters;Nov2006, Vol. 15 Issue 6, p15 

    The article discusses a research paper about sentinel lymph node biopsy (SNB). It highlights that the incidence of lymphedema in the breast cancer population is decreasing with the advent of sentinel node biopsy. The study involves 1,033 patients randomized to the SNB group or the standard...

  • Comparison of early onset breast cancer patients to older premenopausal breast cancer patients. Varga, Dominic; Koenig, Jochem; Kuhr, Kathrin; Strunz, Kathrin; Geyer, Verena; Kurzeder, Christian; Atassi, Ziad; Blettner, Maria; Kreienberg, Rolf; Woeckel, Achim // Archives of Gynecology & Obstetrics;Dec2010, Vol. 282 Issue 4, p427 

    Background: The objective of this study was to show differences between breast cancer patients ≤35 and >35 years with regard to tumor characteristics and to present the patient-relevant outcomes overall survival (OAS) and recurrence-free survival (RFS). Methods: We analyzed data from 119...

  • Changing Trends of Breast Cancer Survival in Sultanate of Oman. Kumar, Shiyam; Burney, Ikram A.; Al-Ajmi, Adel; Al-Moundhri, Mansour S. // Journal of Oncology;2011, p1 

    Breast cancer is the leading cause of cancer-associated mortality in women, with elevated incidence in developing countries. This retrospective study included all 122 patients diagnosed with breast cancer from January 2003 to December 2008 in the Sultanate of Oman. Age at presentation was 47.41...

  • Chest lymphedema after breast cancer treatment. De Godoy, Jose Maria Pereira; Barufi, Stelamarys; Maria de Fatima Guerreiro Godoy, OT. // Journal of Phlebology & Lymphology;2012, Vol. 5, p22 

    One of the main complications in the treatment of breast cancer is lymphedema. The tests are more specific for the diagnosis of lymphedema in the extremities, though the lymphatic drainage of the chest is also compromised and in need. The aim of the current study was to evaluate the prevalence...

  • Whether drainage should be used after surgery for breast cancer? A systematic review of randomized controlled trials. He, Xiao-Dong; Guo, Zhi-Hui; Tian, Jin-Hui; Yang, Ke-Hu; Xie, Xiao-Dong // Medical Oncology;Dec2011, Vol. 28, p22 

    A systematic review of randomized controlled trials (RCTs) was conducted to evaluate whether patients benefit from the suction drainage after axillary lymph node dissection (ALND) in breast cancer surgery. RCTs of drainage versus no drainage after ALND in women with breast cancer were retrieved...

  • Breast cancer-related lymphoedema: implications for primary care. Harmer, Victoria // British Journal of Community Nursing;Oct2009 Supplement, Vol. 14, pS15 

    As more women are surviving breast cancer, long-term complications of treatment that affect quality of life, such as lymphoedema, gain greater importance (Tsai et al, 2009). The various approaches to treating lymphoedema include skin care, elevation of the affected arm, the use of compression...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics