Interactions Between Commensal Bacteria and Gut Sensorimotor Function in Health and Disease

Barbara, Giovanni; Stanghellini, Vincenzo; Brandi, Giovanni; Cremon, Cesare; Nardo, Giovanni Di; De Giorgio, Roberto; Corinaldesi, Roberto
November 2005
American Journal of Gastroenterology;Nov2005, Vol. 100 Issue 11, p2560
Academic Journal
Commensal bacteria inhabiting the human intestine ( i.e., intestinal microflora) participate in the development and maintenance of gut sensory and motor functions, including the promotion of intestinal propulsive activity. On the other hand, intestinal motility represents one of the major control systems of gut microflora, through the sweeping of excessive bacteria from the lumen. There is emerging evidence indicating that changes in this bidirectional interplay contribute to the pathogenesis of gut diseases, such as small intestinal bacterial overgrowth and intestinal pseudo-obstruction. Recent interest has also been directed to the potential role of intestinal microflora in the pathogenesis of the irritable bowel syndrome. Although the status of intestinal microflora in the irritable bowel syndrome remains unsettled, small intestinal bacterial overgrowth (as detected with breath testing) and increased fermentation of foods with gas production, provide indirect evidence that microflora may contribute to symptom generation in irritable bowel syndrome. The potential benefit of antibiotic and probiotic therapy is currently under investigation and opens new perspectives in irritable bowel syndrome treatment.


Related Articles

  • Post-Diarrhea Chronic Intestinal Symptoms and Irritable Bowel Syndrome in North American Travelers to Mexico. Okhuysen, Pablo C.; Jiang, Zhi Dong; Carlin, Lily; Forbes, Charles; DuPont, Herbert L. // American Journal of Gastroenterology;Sep2004, Vol. 99 Issue 9, p1774 

    OBJECTIVES: Irritable bowel syndrome (IBS) has been reported to complicate bacterial diarrhea. Because of the frequency of international travel and the common occurrence of bacterial diarrhea, we studied the occurrence of chronic gastrointestinal complaints and post-diarrhea IBS in North U.S....

  • Food and Irritable Bowel Syndrome.  // Total Health;Jan/Feb2006, Vol. 27 Issue 6, p38 

    This article offers information on the irritable bowel syndrome (IBS). IBS is characterized by cramps, bloating, constipation, and diarrhea. However, IBS does not harm the intestines or result in intestinal bleeding or cancer. It is not fully understood why some people suffer from IBS. As such,...

  • ABSTRACTS FOR GASTROENTEROLOGISTS. Van Der Reis, Leo; Eisenstadt, H. B.; Cane, Walter; DePrizio, Carl J.; Walther, Joseph E.; Baird Jr., William L.; Lazar, Alexander J.; Susinno, A. M. // American Journal of Gastroenterology;Jan1967, Vol. 47 Issue 1, p75 

    Presents abstracts of studies on gastroenterology, published in various medical journals in 1966. "The Pancreozymin-Secretin Test After Partial Gastrectomy," by D. C. McGillivray et al., published on the June 11 issue of the "Canadian Medical Association Journal"; "Postgastrectomy Syndromes," by...

  • ABSTRACTS FOR GASTROENTEROLOGISTS. Ficarra, Bernard J.; Schwartz, Saul A.; Gilbert, Samuel M.; Immerman, Samuel L.; Ledbetter, Paul; Marks, Lionel; Brown, J. Edward; DePrizio, Carl J.; Bernstein, Abraham; Joseph, Hans J.; McMahon, John M.; Cane, Walter; Susinno, A. M.; Walther, Joseph E.; Cohen, Theodore; Epstein, Ezra J. // American Journal of Gastroenterology;Jan1965, Vol. 43 Issue 1, p62 

    Presents several abstracts of studies in the field of gastroenterology. "Abdominal Complications of Anticoagulant Therapy," by J. W. E. Raine; "Reticulum Cell Sarcoma of the Ileum with Perforation: Report of A Case," by John Harrington Tanous; "Problems of Total Colectomy," by J. A. Pinckaers.

  • You Can Conquer IBS. Moore, Arden; Pumphrey, Jaime // Prevention;Aug2000, Vol. 52 Issue 8, p144 

    Reports on research being done on irritable bowel syndrome (IBS). List of symptoms; Difficulty in diagnosing IBS; Theories on what causes IBS; Prescriptions and natural remedies used to treat IBS. INSET: Let Your Mind Ease the Pain in Your Gut.

  • Managing symptoms key to living with IBS. PRATT, TIMOTHY // South County Journal;4/24/2013, Vol. 48 Issue 17, pB2 

    The article offers suggestions for dealing with Irritable Bowel Syndrome (IBS), a digestive system disorder, with primary focus on symptom management.

  • IN COMING ISSUES.  // American Journal of Gastroenterology;Sep1974, Vol. 62 Issue 3, p296 

    Presents information on the in coming issues of "The American Journal of Gastroenterology."

  • ABSTRACTS FOR GASTROENTEROLOGISTS. Dyne, Joseph R. Van; Svigals, Chester S.; Billingsley Jr., Wm K. // American Journal of Gastroenterology;Oct1956, Vol. 26 Issue 4, p510 

    Presents several abstracts on gastroenterology. "The Upper Midline Abdominal Incision," by Millington O. Young; "Possible Recurrent Secondary Omental Torsion," by Orland B. Scott; Acute and Chronic Jejunogastric Intussusception," by William S. Caudell and C. Marshall Lee Jr.; "Duodenal Atresia...

  • JSGE special centennial issue. Sato, Nobuhiro // Journal of Gastroenterology;2000 Supplement 12, Vol. 35, Preceding p1 

    Presents an introduction to articles in the December 2, 2000 issue of a journal on gastroenterology. Foundation of gastroenterology study; Diagnosis and treatment of gastrointestinal cancer.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics