Images in Thorax: Cystic lung lesions as an immune reconstitution inflammatory syndrome (IRIS) in HIV-TB co-infection?

Richardson, D.; Rubinstein, L.; Ross, E.; Rice, A.; R.Wright, A.; Kon, O. M.; Walsh, J.
October 2005
Thorax;Oct2005, Vol. 60 Issue 10, p884
Academic Journal
The article discusses the case of a 33 year old man who was presented with a 3 week history of night sweats, fever, productive cough, and intermittent headaches. He was found to be HIV antibody positive and fully sensitive Mycobacterium tuberculosis was cultured from his cerebrospinal fluid, blood, and bronchoalveolar lavage fluid. Standard antituberculous treatment was commenced and he improved clinically. Four weeks later anti-HIV treatment was introduced. He became febrile again and his clinical status deteriorated with fevers up to 40 degree Celsius, weight loss, and increased acute phase responses.


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