LUNG ALERT: A clinic service offering isoniazid preventive therapy to HIV infected adults reduces the incidence of tuberculosis

Khan, A. R.
October 2005
Thorax;Oct2005, Vol. 60 Issue 10, p809
Academic Journal
The article cites a study which reports on isoniazid preventive therapy to HIV infected adults. This study followed 1655 HIV infected male employees of a South African gold mining company for a median duration of 22.1 months. Isoniazid preventive therapy, 300 mg daily, was offered at clinic enrolment to 679 subjects who attended with no evidence of active tuberculosis. A total of 254 TB episodes met the study criteria. Despite the reduction, the incidence rate is still high at 9 per 100 person-years.


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