Perinatal Complications of Assisted Reproduction

Aboulghar, Mohamed A.
October 2005
Croatian Medical Journal;2005, Vol. 46 Issue 5, p751
Academic Journal
The main perinatal complications of assisted reproduction include congenital malformation, chromosomal aberrations, multiple pregnancy, and prematurity. Earlier studies and in vitro fertilization (IVF) registries showed that there was no increased incidence of congenital malformations in children conceived by IVF/intracytoplasmic sperm injection (ICSI). However, a large Australian study has found that by one year of age, the incidence of congenital malformations in IVF/ICSI children is increased in comparison with those naturally conceived. Several investigators found a slight but increased risk of chromosomal aberrations in ICSI children. Multiple pregnancy is a major cause of increased perinatal mortality due to increased incidence of both prematurity and congenital malformations. Even in singleton pregnancies conceived by assisted reproductive technologies, the risk of prematurity and newborns small for gestational age is increased. In this article, recently published work on perinatal complications associated with assisted reproductive technologies is reviewed.


Related Articles

  • Single Embryo Transfer: Double Remedy for Complications After Assisted Reproduction. Delbaere, Ilse; De Sutter, Petra; Gerris, Jan; Temmerman, Marleen // Current Women's Health Reviews;2008, Vol. 4 Issue 4, p218 

    Thanks to assisted reproductive technologies (ART), the majority of subfertile couples are no longer set aside from one of the deepest desires mankind has in life. However, since the early days of ART - application, two major disadvantages derived. First, the transfer of multiple embryos in...

  • Reply: The danger of ignoring pregnancy and delivery rates in ART. De Neubourg, D.; Bogaerts, K.; Wyns, C.; Camus, M.; Delbaere, A.; Delvigne, A.; De Sutter, P.; Dubois, M.; Gordts, S.; Lejeune, B.; Leroy, F.; Vandekerckhove, F.; D'Hooghe, T. // Human Reproduction;Aug2014, Vol. 29 Issue 8, p1830 

    No abstract available.

  • Management of Multiple Pregnancy. Dudenhausen, Joachim W. // Donald School Journal of Ultrasound in Obstetrics & Gynecology;Jul-Sep2009, Vol. 3 Issue 3, p45 

    Background: Changing delivery age and successes in reproductive have medicine induced an increase in incidence of the multiples in the industrialized world. Methods: Selective literature research was performed complemented by the autor's clinical experience and national and international...

  • Perinatal Problems in Multiple Births. Dudenhausen, Joachim W.; Maier, Rolf F. // Deutsches Aerzteblatt International;9/24/2010, Vol. 107 Issue 38, p2 

    The article discusses the perinatal complications in women with multiple pregnancies. It is said that pregnancies in women have increased after 1990 mainly due to the developments in reproductive medicine, such as induced ovulation and in vitro fertilization (IVF). In multiple pregnancies the...

  • Hydroxyprogesterone does not prevent preterm delivery of twins.  // Reactions Weekly;2/23/2013, Issue 1440, p3 

    The article presents the findings of a French research presented at the Society for Maternal-Fetal Medicine (SMFM) on the effectiveness of 17-α-hydroxyprogesterone caproate in preventing preterm birth among women with twin pregnancies.

  • Leveling with patients about the risks of ART. Scoccia, Bert // Contemporary OB/GYN;Nov2006, Vol. 51 Issue 11, p90 

    The article discusses the risks associated with assisted reproductive technologies (ART). Brief history of ART is presented. The maternal risks associated with ART are described, including higher-order multiples, ovarian hyperstimulation syndrome and ectopic pregnancy. Fetal risks in ART include...

  • Obstetric and perinatal outcome of 1655 ICSI and 3974 IVF singleton and 1102 ICSI and 2901 IVF twin births: a comparative analysis. Ombelet, Willem; Cadron, Isabelle; Gerris, Jan; De Sutter, Petra; Bosmans, Eugene; Martens, Guy; Ruyssinck, Gunther; Defoort, Paul; Molenberghs, Geert; Gyselaers, Wilfried // Reproductive BioMedicine Online (Reproductive Healthcare Limited;Jul2005, Vol. 11 Issue 1, p76 

    A total of 3974 IVF and 1655 ICSI singleton births and 2901 IVF and 1102 ICSI twin births were evaluated. Pregnancies after both fresh and frozen transfers were included. IVF and ICSI singleton pregnancies were very similar for most obstetric and perinatal variables. The only significant...

  • Incidence and complications of multiple gestation in Canada: proceedings of an expert meeting.  // Reproductive BioMedicine Online (Reproductive Healthcare Limited;Jun2007, Vol. 14 Issue 6, p773 

    This paper reports the proceedings of a consensus meeting on the incidence and complications of multiple gestation in Canada. In addition to background presentations about current and possible future practice in Canada, the expert panel also developed a set of consensus points. The need for...

  • Overview. Preterm labour: mechanisms and management. Bernal, Andrés López // BMC Pregnancy & Childbirth;2007 Supplement 1, Vol. 7, pS2 

    Preterm birth remains a major cause of perinatal mortality and long term handicap in surviving infants. This is one of the most important clinical problems in Europe and across the world. While some preterm births are iatrogenic, associated with severe complications of pregnancy (e.g....


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics