TITLE

ONCE-DAILY AMOXICILLIN FOR STREPTOCCAL PHARYNGITIS IN CHILDREN

AUTHOR(S)
Adelman, Alan
PUB. DATE
April 1999
SOURCE
Journal of Family Practice;Apr1999, Vol. 48 Issue 4, p253
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article cites a research study that analyzes whether once-daily therapy with amoxicillin is an effective treatment for children with streptococcal pharyngitis. Group A beta-hemolytic streptococcus (GABHS) pharyngitis remains a fairly common problem for family physicians. Although twice-daily dosing is acceptable in adults, the standard dosing schedule for the pediatric population is 4 times a day. Once-daily dosing would be easier, and might lead to better compliance. The U.S. Food and Drug Administration has approved cefadroxil, cefixime, ceftibuten, and azithromycin for once-daily dosing in the treatment of GABHS pharyngitis. The population studied was children with an age of 4 to 18 years with suspected GABHS pharyngitis in a private pediatric practice. Consecutive patients with suspected GABHS pharyngitis were considered for the study. Their throats were swabbed for both a rapid antigen test and culture, and they were randomly assigned to a 10-day course of either 750 mg amoxicillin once per day or 250 mg penicillin V 3 times per day.
ACCESSION #
1846400

 

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