The importance of keeping in touch: regulation of cell-cell contact in the exocrine pancreas

Apte, M. V.; Wilson, J. S.
October 2005
Gut;Oct2005, Vol. 54 Issue 10, p1358
Academic Journal
Presents new insights into the mechanisms regulating acinar cell-cell contact in the exocrine pancreas. Information that the formation of tissues and organs of multicellular organisms during embryonic development involves a highly regulated process of integration and segregation of heterogeneous cell populations into organised cell patterns; Report that one of the major regulators of the processes of cell migration, proliferation, and differentiation during organogenesis is cell-cell adhesion, which is predominantly mediated by cell surface glycoproteins; Information that these cell adhesion proteins can respond to cell signalling events and can also transduce signals into the cell.


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