Melatonin: a novel treatment for IBS?

Elsenbruch, S.
October 2005
Gut;Oct2005, Vol. 54 Issue 10, p1353
Academic Journal
Focuses on the use of melatonin for the treatment of irritable bowel syndrome (IBS). Opinion that studies using electroencephalogram techniques may be useful to reveal disturbed brain activity consistent with the hypothesis of hypervigilance/ altered arousal mechanisms in IBS; Suggestion that reports of night time awakenings due to gastrointestinal symptoms, mainly abdominal or epigastric pain, may be used as a discriminatory factor between organic and functional disorder; Information that a review of the existing literature confirms that a large percentage of IBS patients report sleep disturbances.


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