Review: Good evidence supports polyethylene glycol and tegaserod for constipation

Andrews, Christopher N.; Bharucha, AM E.
September 2005
ACP Journal Club;Sep/Oct2005, Vol. 143 Issue 2, p47
Academic Journal
The article presents information about a study on the efficacy and safety of traditional medical therapies for chronic constipation. The researchers analyzed randomized controlled trials that compared medical therapies with placebo or compared 2 separate agents in adults with constipation. The agents evaluated were osmotic laxatives, irritant and stimulant laxatives, bulk laxatives, softening or wetting agents, and other agents. In patients with constipation, good evidence exists to support the use of polyethylene glycol and tegaserod and moderate evidence supports the use of lactulose and psyllium.


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