TITLE

Amlodipine or lisinopril was not better than chlorthalidone in reducing renal outcomes in hypertension and impaired renal function

AUTHOR(S)
Tonelli, Marcello; McFarlane, Phil
PUB. DATE
September 2005
SOURCE
ACP Journal Club;Sep/Oct2005, Vol. 143 Issue 2, p45
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article focuses on a study by researcher M. Rahman and colleagues, which found that amlodipine or lisinopril was not better than chlorthalidone in reducing renal outcomes in hypertension and impaired renal function. The study found no evidence that the ACE inhibitor lisinopril reduced risk for ESRD in hypertensive patients at high risk for cardiovascular events more than other classes of antihypertensive agents. Based on evidence from overlapping randomized trials, ACE inhibitors and angiotensin-receptor blockers are recommended for first-line management of hypertension in patients with proteinuric kidney disease or diabetic nephropathy.
ACCESSION #
18427116

 

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