TITLE

Review: Low-dose dopamine does not reduce mortality or need for renal replacement therapy

AUTHOR(S)
Qushmag, Ismael; Cook, Deborah
PUB. DATE
September 2005
SOURCE
ACP Journal Club;Sep/Oct2005, Vol. 143 Issue 2, p42
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article focuses on a study by researcher J.O. Friedrich and colleagues, which reports that low-dose dopamine does not reduce mortality or need for renal replacement therapy. The study reports on the meta-analysis of 61 randomized or quasirandomized trials enrolling 3359 patients. Among trials reporting mortality or need for renal replacement therapy, no effect was found. Among trials focused on physiologic outcomes, urine output was increased, serum creatinine was decreased, and creatinine clearance was transiently increased only after 24 hours of infusion.
ACCESSION #
18427113

 

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