Atorvastatin at 80 mg/d reduced major cardiovascular events more than atorvastatin at 10 mg/d in stable coronary heart disease

Davidson, Michael H.
September 2005
ACP Journal Club;Sep/Oct2005, Vol. 143 Issue 2, p38
Academic Journal
The article presents an answer to a clinical question related to the comparison of the effectiveness of intensive atorvastatin therapy in patients with coronary heart disease (CHD), with moderate atorvastatin therapy for reducing major cardiovascular events. This study included 10,001 patients 35 to 75 years of age who had clinically evident CHD and low-density lipoprotein. Exclusion criteria included hypersensitivity to statins, active liver disease, pregnancy, and uncontrolled diabetes mellitus.


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