TITLE

Hyperperfusion on Perfusion Computed Tomography Following Revascularization for Acute Stroke

AUTHOR(S)
Nguyen, T. B.; Lum, C.; Eastwood, J. D.; Stys, P. K.; Hogan, M.; Goyal, M.
PUB. DATE
September 2005
SOURCE
Acta Radiologica;Sep2005, Vol. 46 Issue 6, p610
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Purpose: To describe the findings of hyperperfusion on perfusion computed tomography (CT) in four patients following revascularization for acute stroke. Material and Methods: In 2002–2003, among a series of 6 patients presenting with an acute stroke and treated with intra‐arterial thrombolysis, we observed the presence of hyperperfusion in 3 patients on the follow‐up CT perfusion. We included an additional patient who was treated with intravenous thrombolysis and who had hyperperfusion on the follow‐up CT perfusion. We retrospectively analyzed their CT perfusion maps. Cerebral blood volume (CBV) and cerebral blood flow (CBF) maps were compared between the affected territory and the normal contralateral hemisphere. Results: In the four patients, the mean CBV and CBF were 3.6±2.0 ml/100 g and 39±25 ml/100 g/min in the affected territory compared to the normal side (mean CBV = 2.7±2.1 ml/100 g, mean CBF = 27±23 ml/100 g/min). There was no intracranial hemorrhage in the hyperperfused territories. At follow‐up CT, some hyperperfused brain areas progressed to infarction, while others retained normal white to gray matter differentiation. Conclusion: CT perfusion can demonstrate hyperperfusion, which can be seen in an ischemic brain territory following recanalization.
ACCESSION #
18397032

 

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