TITLE

Relieve dyspepsia, reduce health service costs

PUB. DATE
December 2004
SOURCE
Gut;Dec2004, Vol. 53 Issue 12, p1718
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
This article focuses on the study "Empiric Treatment With high and Standard Dose of Omeprazole in General Practice: Two-Week Randomized Placebo-Controlled Trial and 12-Month Follow-Up of Health-Care Consumption," conducted by V. Meineche-Schmidt, published in the "American Journal of Gastroenterology." Empirical proton pump inhibitor (PPI) therapy has been recommended as an appropriate management strategy for uninvestigated dyspepsia. There is a relative paucity of randomized trial data on the optimum dose of PPI in this patient group and little information on long-term health economic outcomes. The study suggests that the "PPI test" may be useful as patients are reassured that their symptoms are due to an acid related disorder and require less investigation.
ACCESSION #
18384806

 

Related Articles

  • PPI can help mask tumours in dyspepsia.  // Pulse;10/19/2011, Vol. 71 Issue 34, p14 

    The article offers tips on the use of proton pump inhibitor (PPI) in patient with dyspepsia.

  • PPIs and clopidogrel.  // Critical Care Alert;May2009 Pharmacology Watch, p2 

    The article focuses on the efficiency of proton pump inhibitors (PPIs) in reducing the effect of clopidogrel on platelet aggregate.

  • Economic analysis of on-demand maintenance therapy with proton pump inhibitors in patients with non-erosive reflux disease. Hughes, Dyfrig A.; Bodger, Keith; Bytzer, Peter; de Herdt, Dirk; Dubois, Dominique // PharmacoEconomics;2005, Vol. 23 Issue 10, p1031 

    Aim: To evaluate the costs and effectiveness of on-demand maintenance therapy with oral esomeprazole, lansoprazole, omeprazole, pantoprazole or rabeprazole in patients with endoscopy-confirmed non-erosive reflux disease (NERD) in the UK.Methods: A probabilistic model...

  • EXTENDED USE OF PPIs. HONK, CHERIE; Campbell, Eileen F. // Clinical Advisor;Aug2011, Vol. 14 Issue 8, p61 

    The article provides an answer to a question on the effects of taking proton pump inhibitors (PPIs) over an extended period of time.

  • LATELINES.  // Drug Topics;8/6/2001, Vol. 145 Issue 15, p5 

    Presents news briefs in the United States related to health and drugs, as of August 2001. Clearance received by a drug maker to market ribavirin capsules; Changes made on the packaging of Aciphex proton pump inhibitor; Details of a proposed legislation to use cigarette tax in funding SeniorCare...

  • The Therapeutic and Diagnostic Value of 2-week High Dose Proton Pump Inhibitor Treatment in Overlapping Non-erosive Gastroesophageal Reflux Disease and Functional Dyspepsia Patients. Kriengkirakul, Chatchai; Patcharatrakul, Tanisa; Gonlachanvit, Sutep // Journal of Neurogastroenterology & Motility;2012, Vol. 18 Issue 2, p174 

    Background/Aims To evaluate the value of a 2-week high dose proton pump inhibitor (PPI) treatment on patients with overlapping non-erosive gastroesophageal reflux disease (NERD) and functional dyspepsia (FD). Methods Sixty overlapping NERD and FD patients with symptom onset > 3 months prior...

  • Comparative Drug Effects: The Case of GERD Therapies. Wertheimer, Albert I.; Wilson, James M. // Disease Management;Feb2007, Vol. 10 Issue 1, p46 

    The results of clinical trials and approved Food and Drug Administration Drug Applications inform decision makers that a drug was effective in its labeled indications without causing unacceptable side effects. But purchasers for large medical organizations and members of health insurer or...

  • Managing gastroesophageal reflux disease - comparative efficacy and outcomes of dexlansoprazole MR. Frye, Jeanetta W.; Peura, David A. // Therapeutics & Clinical Risk Management;2015, Vol. 11, p1649 

    The management of gastroesophageal reflux disease (GERD) has been revolutionized with the development of proton pump inhibitors (PPIs). Unfortunately, due to the inherent pharmacokinetic and pharmacodynamic profiles of conventional PPIs, many patients continue to suffer from symptoms related to...

  • Proton pump inhibitors - over-prescribed in a rural community? Shafi, Sadaf; Soomro, Rehmatullah; Abbas, Syed Zafar // Pakistan Journal of Medical Sciences;Mar2011, Vol. 27 Issue 2, p300 

    Objectives: There are specific licensed indications for the use of Proton Pump Inhibitors (PPIs). However it is over-prescribed globally. We performed a study to find out the uses and misuses of this expensive drug in our rural and financially poor population. Methodology: Prospective survey of...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics