A clinical evaluation of the new dialysers

von Harthzsch, Barry; Hoenich, Nicholas A.; Samson, Pamela; Erickson, Jennifer; Ashcroft, Rosalind A.; Kerr, D. N. S.
January 1973
Kidney International;Jan1973, Vol. 3 Issue 1, p35
Academic Journal
Seventeen hemodialysers, studied by one team using the same techniques throughout, are compared in terms of their clearance of urea and creatinine, priming volume, residual blood volume, ultrafiltration rate, handling and cost. Data on clearance of higher molecular weight substances are also presented for six of the dialysers. The Meltec 1 m² Multipoint dialyser has a considerable superiority over the Kiil of the same surface area in clearance of all molecules studied, a higher ultrafiltration rate and similar priming volume, residual blood volume, handling characteristics and cost. Of the disposable dialysers the EX-03. Nephravon, Ultraflo 100 and Ultraflo 2 coils and the Dasco SP 400, Gambro Lundia and Rhone Poulenc 1D parallel flow dialysers all have urea and creatinine clearances superior to the Kiil. There are small differences in performance between members of this group but they are counterbalanced by differences in priming volume, flexibility of ultrafiltration, ease of handling, leakage rate and cost. Thus there is no single disposable dialyser which has a clearcut superiority over its rivals. The Cordis HFAK. has a considerably higher urea and creatinine clearance than any other disposable dialyser but its clearance of large molecules is lower and its residual blood volume higher when compared to the Kiil.


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