P53 gene (Gendicine) and embolisation overcame recurrent hepatocellular carcinoma

Guan, Y. S.; Liu, Y.; Zhou, X. P.; Li, X.; He, Q.; Sun, L.
September 2005
Gut;Sep2005, Vol. 54 Issue 9, p1318
Academic Journal
Transcatheter arterial chemoembolisation (TACE) has become the standard treatment for unresctable hepatocellular carcinoma (HCC). However, this method is often unsuccessful. The p53 gene, which is present as a mutant form in many human tumours, is known to have broad spectrum antitumour effects when expressed normally. In this study, we report a 23 year old patient with recurrent HCC who was treated with the p53. gene (Gendicine) combining TACE, which resulted in a good clinical prognosis.


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