TITLE

Epidemiological and Microbiological Diagnosis of Suppurative Keratitis in Gangetic West Bengal, Eastern India

AUTHOR(S)
Basak, Samar K.; Basak, Sukumar; Mohanta, Ayan; Bhowmick, Arup
PUB. DATE
March 2005
SOURCE
Indian Journal of Ophthalmology;Mar2005, Vol. 53 Issue 1, p17
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Purpose: To determine the epidemiologcial pattern and risk factors involved in suppurative corneal ulceration in Gangetic West Bengal, eastern India, and to identify the specific microbial agents responsible for corneal infections. Methods: All patients with suspected microbial keratitis presenting to the corneal clinic at Disha Eye Hospital, Barrackpore, West Bengal, India, from January 2001 to December 2003 were evaluated. Sociodemographic data and information pertaining to the risk factors were recorded. After diagnosing infective corneal ulcer clinically, corneal scraping and cultures were performed. Results: Over a three-year period, 1198 patients with suppurative keratitis were evaluated. Ocular trauma was the most common predisposing factor in 994 (82.9%) patients (P<0.0001), followed by use of topical corticosteroids in 231 (19.28%) patients. Cultures were positive in 811 (67.7%) patients. Among these culture positive cases, 509 (62.7%) patients had pure fungal infections (P<0.001), 184 (22.7%) patients had pure bacterial infections and 114 (14.1%) had mixed fungal with bacterial infections. Acanthamoeba was detected in 4 (0.49%) patients. The most common fungal pathogen was Aspergillus spp representing 373 (59.8%) of all positive fungal cultures (P<0.0001), followed by Fusarium spp in 132 (21.2%) instances. Most common bacterial isolate was Staphylococcus aureus, representing 127 (42.6%) of all the bacterial culture (P<0.0001) followed by Pseudomonas spp 63 (21.1%). Conclusion: Suppurative keratitis in Gangetic West Bengal, most often occurs after a superficial corneal trauma with vegetative or organic materials. Fungal ulcers are more common than bacterial ulcers. Aspergillus spp and Staphylococcus aureus were the most common fungus and bacteria respectively. These 'regional' findings have important public health implications for the treatment and prevention of suppurative corneal ulceration in this region of India.
ACCESSION #
18102236

 

Related Articles

  • Aspergillus keratitis following corneal foreign body. Fahad, B.; McKellar, M.; Armstrong, M.; Denning, D.; Tullo, A. // British Journal of Ophthalmology;Jun2004, Vol. 88 Issue 6, p847 

    Recognition, diagnosis, and management of fungal keratitis remain difficult despite significant advances in understanding of the disease. Most fungal keratitis is caused by filamentous fungi with the epidemiology varying throughout the world. It is believed to be rare in Great Britain,...

  • Double-Check the Diagnosis.  // Review of Optometry;1/15/2008, Vol. 145 Issue 1, p79 

    The article provides an answer to a question on how to treat a patient with dendriform keratitis which is getting worse with topical steroid therapy.

  • Pilot study highlights potential of corneal cross-linking for treating infectious keratitis. Bechtel, Bryan; Hasson, Matthew; Preston, Courtney // Ocular Surgery News Europe;May2010, Vol. 21 Issue 5, p17 

    The article discusses a study which highlights the possible use of corneal cross-linking in the treatment of patients with infectious keratitis.

  • Archives of Ophthalmology.  // Biomedical Market Newsletter;4/14/2012, Vol. 21, p1 

    The article offers information on a study which revealed that the thickness of cornea varies in the early stages of Fuchs' Endothelial Corneal Dystrophy.

  • Perfil epidemiológico das ceratomicoses atendidas no HC-UNICAMP. MÜLLER, GUILHERME GUBERT; KARA-JOSÉ, NEWTON; DE CASTRO, ROSANE SILVESTRE // Arquivos Brasileiros de Oftalmologia;2012, Vol. 75 Issue 4, p247 

    Background: Fungal keratitis is an important cause of corneal infection mainly in tropical countries. With high morbidity due to delay in diagnosis, laboratory examination is mandatory in these cases. However, technical difficulties in obtaining samples generate a large number of false...

  • Herpes Simplex Virus in Ocular, Nasal, and Oral Secretions of Patients with Herpetic Keratitis. BRIGHTMAN, V. J. F.; HART, D. R. L.; READSIAW, G. G.; PORTER, G. T. J.; TULLY, M. J. // Journal of Dental Research;Jan1966, Vol. 45 Issue 1, p178 

    No abstract available.

  • Type of soap, UV light boost incidence of DLK. Charters, Lynda; Kershner, Robert // Ophthalmology Times;10/01/2000, Vol. 25 Issue 19, p16 

    Focuses on diffuse lamellar keratitis (DLK). Procedures done to eliminate possible etiologies of DLK; Background of the occurrence of DLK; Contributing factors.

  • Intrastromal corneal ring segments associated with low incidence of acute microbial keratitis. Boyle, Erin L.; Hasson, Matt // Ocular Surgery News;8/10/2010, Vol. 28 Issue 15, p18 

    The article discusses research done on the association between intrastromal corneal ring segments and low incidence of acute microbial keratitis, published in the 2010 issue of the "Journal of Refractive Surgery."

  • Thygeson's disease.  // Taber's Cyclopedic Medical Dictionary (2009);2009, Issue 21, p2317 

    A definition of the term "Thygeson's disease," which refers to bilateral corneal inflammation of unknown cause, is presented.

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics