Inhaled corticosteroids did not increase nonvertebral fractures in adults with asthma or chronic obstructive pulmonary disease

Thien, Frank
July 2005
ACP Journal Club;Jul/Aug2005, Vol. 143 Issue 1, p53
Academic Journal
This article presents information on a study describing the risk of nonvertebral fracture related to inhaled corticosteroid (ICSs) exposure among adults with chronic respiratory disease. In adults with asthma, chronic obstructive pulmonary disease, or both, short-term use of inhaled corticosteroids at recommended doses did not increase the risk for nonvertebral fractures. ICS exposure was identified from pharmacy claims occurring in the year before the index date. All ICSs were grouped together as a class, but also evaluated separately or in combination with beta-agonists. Covariates included demographic variables and type of underlying respiratory disease.


Related Articles

  • Evaluation Of The Bronchodilator Effect And Side Effect Profile Of A Salbutamol Dry Powder Inhaler Device: A Prospective Observational Study. Toit, G. Du; Brown, G.; Joshua, B.; Motala, C.; Nell, H.; Weinberg, E.G. // Internet Journal of Pediatrics & Neonatology;2004, Vol. 4 Issue 1, p22 

    Dry Powder Inhalation devices are currently used for the administration of inhaled Corticosteroids (ICS) and short acting B2 agonists (SABA). Most generic asthma medications are only available as Metered Dose Inhalers (MDI), with the consequence that Dry Powder Inhaler (DPI) devices are...

  • Early Administration of Corticosteroids in Emergency Room Treatment of Acute Asthma. Stein, Lawrence M.; Cole, Randolph P. // Annals of Internal Medicine;6/1/90, Vol. 112 Issue 11, p822 

    Presents a study that determined the effect of early administration of high-dose intravenous corticosteroids on duration of emergency room treatment and hospital admission rate in patients with acute asthma. Characteristics of control and steroid groups; Average duration of emergency room...

  • Evaluation of the left and right ventricular systolic and diastolic function in asthmatic children. Akyüz Özkan, Esra; Khosroshahi, Hashem E. // BMC Cardiovascular Disorders;7/8/2016, Vol. 16, p1 

    Background: Asthma is the most common cause of respiratory disorders among children. We aimed to investigate left (LV) and right (RV) ventricular function in asthmatic children as detected by conventional and tissue Doppler echocardiography.Methods: Fifty pediatric...

  • Antagonism of tumour necrosis factor α in refractory asthma. Berry, Mike A.; Pavord, Ian D. // Thorax;Jul2008, Vol. 63 Issue 7, p571 

    The author reflects on the antagonism of tumor necrosis factor in α in refractory asthma. He states that asthma that is refractory to treatment with inhaled corticosteroids affects 5-10 percent of patients with asthma. The author further states that the rationale for investigating the role of...

  • New combination treatments in the management of asthma: focus on fluticasone/vilanterol. Tan, Laren D.; Chan, Andrew L.; EAlbertson, Timothy E. // Journal of Asthma & Allergy;2014, Vol. 7, p77 

    Despite the 2007 National Asthma Education and Prevention Program Expert Panel 3 guidelines for the treatment of uncontrolled asthma, many patients with poorly controlled asthma still continue to tax the health care system. Controlling asthma symptoms and preventing acute exacerbations have been...

  • Treating patients with asthma who are dependent on systemic steroids. Shiner, R.J.; Geddes, D.M. // BMJ: British Medical Journal (International Edition);7/22/89, Vol. 298 Issue 6693, p216 

    Discusses the treatment of patients with asthma dependent on systemic corticosteroids. Side effects of corticosteroids; Correlation between the reduction in dose and responsiveness to methacholine; Assessment of inhaled steroids.

  • Prednisone.  // Reactions Weekly;1/19/2008, Issue 1185, p26 

    The article describes a case of pulmonary nocardiosis in a chronic corticosteroid user. A 49-year-old man was receiving prednisone for his idiopathic thrombocytopenic purpura. Some of the symptoms presented by the patient consistent with pulmonary nocardiosis include loss of appetite, pain when...

  • The Oxidant-Antioxidant Balance in Mild Asthmatic Patients. Hanta, I.; Kuleci, S.; Canacankatan, N.; Kocabas, A. // Lung;2003, Vol. 181 Issue 6, p347 

    We investigated the oxidant-antioxidant balance and the effect of inhaled corticosteroids on this balance in mild stable asthmatics. Included in the study were 30 mild asthmatic patients (11 male, 19 female, mean age (year) � SD: 35.1 � 9.7) and 26 healthy adults (7 male, 19 female,...

  • Breathing life into asthma research. Sayburn, Anna // Update;5/19/2005, Vol. 70 Issue 5, p5 

    This article discusses about the papers on asthma. After years in which little seemed to change, the past month has seen two new research papers that offer different ways of thinking about the disease. It has been accepted in the Great Britain that regular use of inhaled corticosteroids is the...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics