Review: Adding long-acting beta2-agonists to inhaled corticosteroids reduces asthma exacerbations more than adding antileukotrienes
- Role of Leukotriene Receptor Antagonists in the Management of Pediatric Asthma. Dumitru, Catalina; Chan, Susan M. H.; Turcanu, Victor // Pediatric Drugs;2012, Vol. 14 Issue 5, p317
At present, the main indications for leukotriene receptor antagonists (LTRA) in pediatric asthma are as add-on therapy to inhaled corticosteroids (ICS) and as initial controller therapy in children with mild asthma, especially those who cannot or will not use ICS. LTRA are also useful for...
- Montelukast: A Viewpoint by Romain A. Pauwels. Pauwels, R.A. // Drugs;Aug1998, Vol. 56 Issue 2, p257
Offers views on the leukotriene antagonist montelukast used for treating asthma. Background on asthma; Effectiveness.
- Inhaled glucocorticoids versus leukotriene receptor antagonists as single agent asthma treatment: systematic review of current evidence. Ducharme, Francine M. // BMJ: British Medical Journal (International Edition);3/22/2003, Vol. 326 Issue 7390, p621
Objective: To compare the safety and efficacy of anti-leukotrienes and inhaled glucocorticoids as monotherapy in people with asthma. Design: Systematic review of randomised controlled trials comparing anti-leukotrienes with inhaled glucocorticoids for 28 days or more in children and adults. Main...
- Pharmacotherapy -- add-on therapies. // CMAJ: Canadian Medical Association Journal;9/13/2005 Supplement, Vol. 173, pS37
The article focuses on the effectiveness regarding the use inhaled corticosteriods (ICS)and leukotriene receptor antagonists (LTRA)as add-on therapy in treating children with asthma. The effectiveness ICS has been compared with long-acting bronchodilators (LABA) such as salmenterol or...
- zafirlukast. Peters, Michael // BMA A-Z Family Medical Encyclopedia;2004, p814
A definition of the term "zafirlukast" is presented. It refers to a leukotriene receptor antagonist. Zafirlukast is used in asthma prevention.
- zafirlukast. // Taber's Cyclopedic Medical Dictionary;2005, p2367
The article presents a definition for the term "zafirlukast," which is a leukotriene inhibitor used for the treatment of asthma.
- Early intervention with low-dose inhaled corticosteroid (ICS) therapy is beneficial in patients with mild persistent asthma. // Drugs & Therapy Perspectives;Apr2008, Vol. 24 Issue 4, p9
Treatment of mild asthma with low-dose inhaled corticosteroids (ICSs) improves control of the disease and prevents disease exacerbation. Early treatment with ICSs appears to diminish, but not completely prevent, the decline in airway function in patients with asthma, although the positive...
- Adrenal Insufficiency in Sepsis. Annane, Djillali // Current Pharmaceutical Design;Jul2008, Vol. 14 Issue 19, p1882
The role of the hypothalamic-pituitary adrenal axis in the host response to infection is crucial. The initial inflammatory response to sepsis activates the endogenous release of cortisol, which in turn modulates the synthesis and release of both pro- and anti-inflammatory mediators to restrict...
- Montelukast. // Reactions Weekly;6/6/2009, Issue 1255, p24
The article describes the case of a 37-year-old woman who developed Churg-Strauss syndrome while being treated with montelukast, a leukotriene receptor antagonist, for possible cough variant asthma. Within 1 month of treatment, the patient's cough began to deteriorate, but she developed dyspnoea...