Pegaptanib was effective and safe without a dose-response relation in neovascular, age-related, macular degeneration

Sullivan, Frank
July 2005
ACP Journal Club;Jul/Aug2005, Vol. 143 Issue 1, p41
Academic Journal
This article presents information on a study related to pegaptanib for neovascular age-related macular degeneration. 1208 patients 50 years of age had subfoveal sites of choroidal neovascularization secondary to age-related, macular degeneration and a range of best corrected visual acuity of 20/40 to 20/320 in the study eye, and 20/800 or better in the other eye. All angiographic subtypes of lesions were eligible if lesions were a total size 12 optic-disk areas. 586 patients were included in 1 trial at 58 sites in the United States and Canada, and 622 patients were included in the other trial at 59 sites in Europe, Israel, Australia, and South America.


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