TITLE

Ximelagatran was not inferior to warfarin for preventing stroke and systemic embolism in nonvalvular atrial fibrillation

AUTHOR(S)
Levi, Marcel
PUB. DATE
July 2005
SOURCE
ACP Journal Club;Jul/Aug2005, Vol. 143 Issue 1, p19
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
This article presents information on a study related to ximelagatran versus warfarin for stroke prevention in patients with nonvalvular atrial fibrillation. Ximelagatran was noninferior to warfarin for preventing the composite endpoint of stroke or systemic embolism. The groups did not differ for rates of myocardial infarction and major bleeding. However, the rate of major and minor bleeding combined was lower in the ximelagatran group than in the warfarin group, and more patients in the ximelagatran group had elevated liver enzymes.
ACCESSION #
18053690

 

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